INTRODUCTION Patients with congenital heart disease frequently require graft material for repair of cardiac defects. However, currently available grafts lack growth potential and are noncontractile and thrombogenic. We have developed a viable cardiac graft that contracts spontaneously in tissue culture by seeding cells derived from fetal rat ventricular muscle into a biodegradable material. We ...

Randomly left or right truncated observations occur when one is concerned with estimation of the distribution of time between two events and when one only observes the time if one of the two events falls in a xed time-window, so that longer survival times have higher probability to be part of the sample than short survival times. In important AIDS-applications the time between seroconversion an...

studies have shown that patients who do not produce donor specific and / or panel reactive anti-hla antibodies have a longer graft survival. the purpose of this study was to evaluate the posttransplant humoral immune response towards hla-class i antigens and the measurement of the serum creatinine levels which are used in monitoring posttransplant function of kidney. serum samples from 132 rena...

conclusions there is a significant increased incidence of mortality, prolonged hospitalization, and rehospitalization in symptomatic patients with severe tr. therefore, we recommend more aggressive approach toward tv repair or replacement in these patients regardless of pap and systolic function. results heart failure (50%) was the most cause of death. mean years of survival from diagnosis of s...

background: colon cancer is the third cause of cancer deaths. although colon cancer survival time has increased in recent years, the mortality rate is still high. the cox model is the most common regression model often used in medical research in survival analysis, but most of the time the effect of at least one of the independent factors changes over time, so the model cannot be used. in the c...

patients and methods we investigated the timing and frequency of acute rejection episodes related to long-term patient-graft survival in taleghani hospital between 1990 and 2011. recipients were divided into three groups as group-1 (no rejection), group-2 (early acute rejection [ear]: less than 3-months) and group-3 (late acute rejection [lar]: after 3 months of transplant). conclusions lar had...

abstract background: breast cancer is the most frequent cancer in women in the western world. with breast cancer now affecting one in ten women, it is important to know how this disease burden is shared among women. aims: this study was undertaken to determine the survival rate of breast cancer in southern iran. methods and material: from december 2001 to december 2006, among 8000 hospital-base...

background: despite advances in the medical care of renal transplant recipients which have led to an improvement in allograft survival, renal allograft rejection is still a major ob-stacle to successful organ transplantation. understanding the mechanisms contributing to allograft rejection will be of great importance for the development of efficient antirejection strategies. objective: the aim ...