Thermally induced ratcheting of a thermo-active pile is the accumulation net and irreversible head displacement upon heating–cooling cycles. Although this kind phenomenon has been observed in vertically loaded piles sand, it unknown whether exists laterally cases, also what underlying mechanisms occur under thermomechanical flexural soil–pile interaction. This study presents series centrifuge t...

Our objective was to evaluate outcomes in patients with sustained viral suppression compared to those with episodes of viremia. Methods. In a prospective cohort of patients started on ART in Uganda and followed for 48 months, patients were categorized according to viral load (VL): (1) sustained-suppression: (VL ≤1,000 copies/mL) (2) VL 1,001-10,000, or (3) VL >10,000. Results. Fifty-Three (11.2...

Slow release testosterone-loaded nanocapsules in alginate, biodegradable hydropolymer, were prepared by in situ nanoemulsion-polymer crosslinking approach. Different formulations varying in the drug loading solvent phase were prepared. Four different drug-loading solvents were assayed and the food grade hexane provided nanocapsules testosterone load of 30%. Testosterone loading was confirmed by...

in the current engineering practices, buildings are commonly designed for an effective lifetime of 50 years. this lifetime can increase the cost of buildings with short lifetimes and can reduce the safety level of buildings with large lifetimes. in this paper, a “service-life factor” has been defined. applying this factor into the nominal values of live, earthquake, wind, and snow loads, the ef...

We simultaneously assessed the blood flow index (BFI) in three respiratory muscles during hyperpnea and high-intensity constant-load cycling sustained at comparable levels of work breathing neural drive patients with COPD. demonstrated that exercise impairs muscle perfusion, as intercostal, scalene, abdominal BFI increased but not cycling. Insufficient adjustment perfusion was associated greate...

Although the accessibility of HIV treatment in developing nations has increased dramatically over the past decade, viral load testing to monitor the response of patients receiving therapy is often unavailable. Existing viral load technologies are often too expensive or resource-intensive for poor settings, and there is no appropriate HIV viral load test currently available at the point-of-care ...

It is generally recognized that heavy timber in fire conditions demonstrates high structural performance. Exposed timber chars which functions as an isolative layer which protects the inner material from heat and loss of load bearing capacity. Char has no significant strength, and therefore, as the char layer grows, the load bearing capacity of the timber member reduces under sustained fire con...

Sleep deprivation can result in degradation of sustained attention through increased distraction by task-irrelevant exogenous stimuli. However, attentional failures in the sleep-deprived state could also be a result of task-unrelated thoughts (TUTs, or mind wandering). Here, well-rested and sleep-deprived participants performed a visual search task under high and low perceptual load conditions....

Working memory (WM) maintenance is assumed to rely on a single sustained process throughout the entire maintenance period. This assumption, although fundamental, has never been tested. We used intracranial electroencephalography (EEG) recordings from the human hippocampus in two independent experiments to investigate the neural dynamics underlying WM maintenance. We observed periodic fluctuatio...