Objective: This study was undertaken to evaluate the effect of vestibular stimulation on motor coordination in Parkinson’s disease (PD) induced mice. Methods: 18 healthy adult male Swiss albino mice were used this study. Vestibule stimulated by caloric (CVS). Pesticide Rotenone induce (PD). Motor assessed fall-off time and activity score using rotarod actophotometer, respectively. Results: In t...

The in vivo protective role of hydro-methanolic root extract of Withania somnifera (WS) was evaluated in alleviating lead nitrate (LN)-induced toxicity in male Swiss albino mice by measuring hematoserological profiles. The lead-treated (20 mg/kg body wt, p.o.) albino mice (25-30 g) concurrently received the root extract (200 and 500 mg/kg body wt, p.o.) once daily for the duration of six weeks....

Diabetes mellitus is a metabolic disorder and affects nearly 10% of the population every year. The aim of present study was to investigate the histological changes in diabetic Induced Swiss albino mice, Mus norvegicus albinus on exposure to 1Deoxynojirimycin. 1-Deoxynojirimycin is known to be a potent antidiabetic compound. The study was conducted on mice Swiss albino male mice, the animals wer...

ETHNOPHARMACOLOGICAL RELEVANCE The plant Cleome gynandra L. (Capparidaceae), is commonly known as 'Hurhur'and 'Karaila' in India and 'Cat's whiskers' in English. Traditionally the whole plant is used in the treatment of tumor, anti-inflammatory and lysosomal stability actions. AIM OF STUDY The objective of present study is to explore the anticancer activity of the methanol extract of the Cleo...

The objective of the present study is to explore the anticancer activity of the ethanolic and aqueous extracts of the Dendrophthoe falcata in Swiss albino mice against Ehrlich Ascites Carcinoma (EAC) cell line. Anticancer activity of ethanolic and aqueous extracts of D. falcata was evaluated in EAC Swiss albino mice at the doses of 200 and 400 mg/kg body weight orally. Both extracts at both dos...

background: in the present investigation radiation and cadmium induced biochemical changes in the kidney of swiss albino mice have been studied. materials and methods: for this purpose, adult male swiss albino mice (6-8 weeks old) were divided into four groups. group i (sham-irradiated), group ii (treated with cdcl2 solution 20 ppm), group iii (irradiated with 1.25, 2.5 and 5.0 gy gamma rays), ...

Objective(s):Gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. In this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. Materials and Methods: Three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (IP) for the evaluation ...