Binding of RecA to poly(dG-m5dC) and poly(dG-dC) under B- and Z-form conditions was studied using circular dichroism (CD) and linear dichroism (LD). LD revealed a quantitative binding of RecA to Mg2+-induced Z-form poly(dG-m5dC) with a stoichiometry of 3.1 base pairs/RecA monomer, which is slightly larger than the 2.7 base pairs observed for the B-form. The LD spectra indicate a preferentially ...

Chemical analysis of metalized DNA has made it quite clear that traditional models thermodynamics are insufficient to predict and control self-assembly in the context orthogonally-paired nucleotides. Recently, there been an increase reports Watson-Crick assembly wires nanostructures [1–4]. The ability add or remove pairing rules between nucleobases toward non-Watson-Crick, orthogonal, alters fu...

The latest memoir of the Society for Endocrinology presents the papers and discussions of a 1958 symposium on selected aspects of comparative and human sex morphology. It is gratifying that discussions of bacteria and invertebrate forms are included. Several authors examine the important question of genetic and hormonal controls of sex differentiation. The possibility of regulating the sex rati...