A precise automated procedure developed for determination of serum lactate dehydrogenase, using the Robot Chemist, measures absorbance of a cuprous-neocuproine complex formed by coupled reduction of the cupric-neocuproine reagent with enzymatically generated reduced nicotinamide adenine dinucleotide. Activity values obtained by this method, by the identical automated colorimetric method on the ...

The general performance of the Technicon AutoAnalyzer II method for the routine estimation of serum aspartate and alanine transaminase has been assessed and compared with that of the LKB reaction rate analyser. The results of the two methods correlate, there is little difference in precision, and running costs are comparable. Some of the relative advantages of the two types of analysis are disc...

This communication concerns two patients in whom spuriously enhanced SGOT (serum glutamic-oxaloacetic transaminase; L-aspartate: 2-oxoglutarate amino-transferase, EC 2.6.1.1), as determined by the SMA 12/60 AutoAnalyzer (Technicon Corp., Tarrytown, N.Y. 10591), led to erroneous diagnoses of liver disease. This error can be avoided by checking suspect supranormal SMA 12/60 values by ultraviolet ...

Electical potentials across the membrane in a modified AutoAnalyzer dialyzer (Technicon) have been determined under various conditions and related to the dialysis of 45Ca. The results suggest that anomalies in the diffusion of calcium from protein and nonprotein containing streams could be due to factors other than "Donnan equilibrium effects."

An automatic method, utilizing the AutoAnalyzer, for titration of influenza virus haemagglutination inhibitors is described. The titres obtained compare favourably with those obtained by densitometric methods. So far, the technique has not proved superior to the densitometric methods in either speed of operation or in reproducibility but various developments are suggested to effect this.

background: automatic cell counter devises make the cbc differential very easy and delivering the results in few second. however, the problem with this device is facing a flag requires a time-consuming microscopic review of the specimen which causes unacceptable wait times for patient as well as costs for laboratories. in this study, we calculated the validity of wbc diff flags in sysmex xt-180...