نتایج جستجو برای: t helper 9
تعداد نتایج: 1132627 فیلتر نتایج به سال:
An experimental condition was established in vivo for selectively eliminating hapten-reactive suppressor T-cell activity generated in mice primed with a para-azobenzoate (PAB)-mouse gamma globulin (MGG)-conjugate and treated with PAB-nonimmunogenic copolymer of D-amino acids (D- glutamic acid and D-lysine; D-GL). The elimination of suppressor T-cell activity with PAB-D-GL treatment from the mix...
The mouse Lyt-1, Lyt-2, and Lyt-3 lymphocyte surface antigens have been used for some years now as immunogenet ic markers whose selective expression distinguishes maturat ional and functional T cell subpopulations (1, 2). Lyt-2 and Lyt-3, for example, are selectively expressed on cytotoxic and suppressor T cells but are not found on helper T cells (3, 4). Similarly, cytotoxic depletion studies ...
The murine model of leishmaniosis is a prototypic example for the critical role played by T helper cells in immunity to pathogens. Cytokines, such as interleukin-12 and interleukin-4, are the major regulatory factors for differentiation of naive T helper cells into T helper 1 and T helper 2 cells, respectively. T helper 1 cells, which are cellular immune mechanisms involving gamma interferon pr...
The phagocytes of the innate immune system, macrophages and neutrophils, contribute to antibacterial defense, but their functional specialization and cooperation is unclear. Here, we report that three distinct phagocyte subsets play highly coordinated roles in bacterial urinary tract infection. Ly6C(-) macrophages acted as tissue-resident sentinels that attracted circulating neutrophils and Ly6...
Mucosal and parenteral immunizations elicit qualitatively distinct immune responses, and there is evidence that mucosal immunization can skew the balance of T helper 1 and T helper 2 responses. However, a clear picture of the effect of the route of infection on the balance of the T helper responses has not yet emerged. Our laboratory previously demonstrated that oral reovirus infection elicits ...
An antigen that clearly marked T helper cells was first identified when the W 3 / 2 5 mouse monoclonal ant ibody was raised against rat thymocytes (1, 2). T h e W 3 / 2 5 antigen appears to be equivalent to human T 4 antigen, which is now called CD4 (3), and to mouse L 3 T 4 antigen (4-6). Hencefor th , we will call the rat ant igen "CD4 (W3/25) ." Antibodies to CD4 antigens inhibit T helper ce...
Comparison of Th1/Th2 and Treg/Th17 ratios between wet and dry cupping therapies in Persian medicine
Objective: In Persian medicine (PM), wet-cupping therapy (WCT) is the most utilized approach. WCT is mostly done between the shoulders, which is referred to as “hejamt-e-aam” in the Persian language. CD4+T cells also refer to T helper lymphocytes play a critical role in the immune system. Naïve CD4+ T cells differentiate into at least four subsets, T helper 1 (Th1), T helper 2 (Th2), T helper 1...
These studies were carried out to investigate the potential helper T cell repertoire specific for the random copolymer poly(L-Glu55,L-Ala35, L-Phe9)n(GL phi 9) of responder, nonresponder, and (responder x nonresponder)F1 murine strains. We tested the ability of these T cells to collaborate with dinitrophenyl (DNP)-specific primary and secondary B lymphocytes of each strain in response to the an...
The mouse Lyt-1, Lyt-2, and Lyt-3 lymphocyte surface antigens have been used for some years now as immunogenet ic markers whose selective expression distinguishes maturat ional and functional T cell subpopulations (1, 2). Lyt-2 and Lyt-3, for example, are selectively expressed on cytotoxic and suppressor T cells but are not found on helper T cells (3, 4). Similarly, cytotoxic depletion studies ...
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