Small silencing RNAs, including microRNAs, endogenous small interfering RNAs (endo-siRNAs) and Piwi-interacting RNAs (piRNAs), have been shown to play important roles in fine-tuning gene expression, defending virus and controlling transposons. Loss of small silencing RNAs or components in their pathways often leads to severe developmental defects, including lethality and sterility. Recently, no...

In this study, iron tailings were used as raw materials mixing with Al2O3, SiO2, and/or CaO sintered at 950–1400 °C to produce glass ceramics. Al2O3/tailing and Al2O3/SiO2/tailing systems, the newly formed crystalline mullite (3Al2O3·2SiO2) reached its maximum content of 83.7 wt% for sample mass ratio 6/2/2. Al2O3/SiO2/CaO/tailing system, anorthite (CaAl2Si2O8) increased 72.9 7/8/4/6 1450 °C. T...

Pipeline transport is commonly used in the oil sand industry to convey crushed ores and tailings. Bitumen residues tailings can be a threat environment that separating them from before disposal crucial. However, low bitumen concentration tailing slurry complex characteristics of four-phase mixture make process difficult. This study establishes an Eulerian–Eulerian (E–E) computational fluid dyna...

Due to economical and environmental issues, utilization of mineral wastes, e.g. iron ore mine tailing (IOMT), as road materials can be recommended as a sustainable alternative. In the present study, mechanical properties, as well as resistance to freezing and thawing cycles (F-T) of low plasticity clay soil stabilized with different percentages of Portland cement (0, 6, 9, 12 and 15%) and diffe...

To finance transportation infrastructure and to address social and environmental negative externalities of road transports, several countries have recently introduced or consider a distance based tax on trucks. In competitive retail and transportation markets, such tax can be expected to lower the demand and thereby reduce CO2 emissions of road transports. However, as we show in this paper, suc...

The static stability evaluation of tailing dam is one of the most important tasks in the mine environmental protection project. The methods for the static stability calculation were discussed in this paper, which were Swedish Circle Method, Janbu Method, Bishop Method, Finite Element Method and Strength Reduction Finite Element Method (SRFEM) with five different failure criterions considered. T...

Ribosomes can stall during translation due to defects in the mRNA template or translation machinery, leading to the production of incomplete proteins. The Ribosome-associated Quality control Complex (RQC) engages stalled ribosomes and targets nascent polypeptides for proteasomal degradation. However, how each RQC component contributes to this process remains unclear. Here we demonstrate that ke...

Physiological aspects of why vetiver grass (Vetiveria zizanioides L.) can be tolerant to heavy metals and be used as an alternative method for rehabilitation of abandoned metalliferous mine wastelands have been investigated. The results showed that high proportions of lead and zinc (Pb/Zn) tailing greatly inhibited the leaf growth, dry matter accumulation, and photosynthesis of leaves, but stim...

Acidic pH is commonly used to elute antibodies from Protein-A affinity column, although low pH may result in aggregation of the proteins. As an alternative, here arginine was tested as an eluent and compared with a more conventional eluent of citrate. Using purified monoclonal antibodies, recovery of antibodies with 0.1M citrate, pH 3.8, was less than 50% and decreased further as the pH was inc...

This study focused on the screening of cadmium-resistant bacterial strains from Pb-Zn tailing. We investigated the diversity of microbial community inhabiting Dong-san-cha Pb-Zn tailing in Beijing, China, by polymerase chain reaction-denaturing gradient gel electrophoresis (DGGE) of 16S rRNA gene of bacterial strain, and found two dominant strains in the DGGE profile. Using special culture medi...