نتایج جستجو برای: tanshinone iia sodium sulfonate tss

تعداد نتایج: 205156  

2015
Mengguo Liu Ji Yang Ming Li

OBJECTIVE Salvia miltiorrhiza has long been used to treat systemic sclerosis. Tanshinone IIA, one of the phytochemicals derived from the roots of Salvia miltiorrhiza, exhibits multiple biological activities. The present study aimed to investigate whether tanshinone IIA has an effect on the interleukin-17A-induced functional activation of systemic sclerosis patient-derived dermal vascular smooth...

2016
LIANQUN JIA NAN SONG GUANLIN YANG YIXIN MA XUETAO LI REN LU HUIMIN CAO NI ZHANG MEILIN ZHU JUNYAN WANG XUE LENG YUAN CAO YING DU YUE XU

Tanshinone IIA is the active compound isolated from Salvia miltiorrhiza bunge, which is a traditional Chinese medicine known as Danshen. The aim of the present study was to assess the effect of Tanshinone IIA on the regulation of lipid metabolism in the livers of hyperlipidemic rats and the underlying molecular events. An in vivo model of hyperlipidemia was established in rats, with the animals...

Journal: :Molecular medicine reports 2012
Xiaoming Zhang Daqiang He Linhao Xu Shucai Ling

Renal preservation is a universal problem since ischemia/reperfusion (I/R) injury remains an unresolved issue during the procedure of renal transplantation. Tanshinone IIA, one of the effective components of the traditional Chinese medicine Danshen, was reported to exhibit a variety of biochemical activities, including protection against I/R injury. Therefore, identifying the specific molecular...

Journal: :Annals of palliative medicine 2021

Background: Alprostadil can effectively dilate blood vessels, improve cardiac microcirculation, and reduce load. Tanshinone IIa injection protect against atherosclerosis myocardial oxygen consumption. However, the effects of alprostadil combined with tanshinone on microcirculation disorder, outcomes, function in patients acute infarction (AMI) after percutaneous coronary intervention (PCI) are ...

2014
Yu-Qing Ma Yi-Rong Chen Yu-Fang Leng Zhi-Wei Wu

Fifty-four Sprague-Dawley rats weighing 200~240 g were randomly divided into sham-operated group (sham group), vehicle-treated SNL group (model group), and Tan IIA-treated SNL group (Tan IIA group). Tan IIA was administered intraperitoneally to rats in the Tan IIA-treated group at a dose of 30 mg/kg daily for 14 days after SNL surgery. Paw withdrawal mechanical thresholds (PWTs) and paw withdra...

Journal: :International journal of oncology 2008
Irina Tsoy Nizamutdinova Gyeong Won Lee Kun Ho Son Su Jin Jeon Sam Sik Kang Yeong Shik Kim Jae Heun Lee Han Geuk Seo Ki Churl Chang Hye Jung Kim

Danshen (Salvia miltiorrhiza Bunge) is a herb that has been widely and successfully used for treating inflammatory diseases in clinics in Asia. The relatively abundant tanshinones, tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone, have been isolated from Danshen. These tanshinones are the major diterpenes isolated from Danshen, and show cytotoxic effects on cell lines deriv...

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