نتایج جستجو برای: tap1

تعداد نتایج: 418  

2015
Ana Patrícia C. Silva Auricélio A. Macêdo Luciana F. Costa Cláudia E. Rocha Luize N. N. Garcia Jade R. D. Farias Priscilla P. R. Gomes Gustavo C. Teixeira Kessler W. J. Fonseca Andréa R. F. Maia Gabriela G. Neves Everton L. Romão Teane M. A. Silva Juliana P. S. Mol Renata M. Oliveira Márcio S. S. Araújo Ernane F. Nascimento Olindo A. Martins-Filho Humberto M. Brandão Tatiane A. Paixão Renato L. Santos Axel Cloeckaert

This study aimed to evaluate protection induced by the vaccine candidate B. ovis ΔabcBA against experimental challenge with wild type B. ovis in rams. Rams were subcutaneously immunized with B. ovis ΔabcBA encapsulated with sterile alginate or with the non encapsulated vaccine strain. Serum, urine, and semen samples were collected during two months after immunization. The rams were then challen...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سیستان و بلوچستان - دانشکده علوم پایه 1393

چکیده: پیشینه تحقیق : اسکیزوفرنی یک اختلال ناتوان کننده عصبی مزمن و پیچیده است که احتمالاً به وسیله¬ی فاکتورهای ژنتیکی و غیره ژنتیکی تحت تأثیر قرار می¬گیرد. میزان شیوع این بیماری در جوامع مختلف بین 7/-1 درصد است و از اهمیت زیادی برخوردار است به همین دلیل مطالعات مختلفی در این زمینه صورت گرفته است . این بیماری نشانگان متنوع و در عین حال تخریب کننده¬ای دارد که تفکر، ادراک، هیجان، حرکت و رفتار فرد...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2013
Filiz Ozbas-Gerceker Nazli Bozman Sevgi Gezici Mustafa Pehlivan Mehmet Yilmaz Sacide Pehlivan Sibel Oguzkan-Balci

Transporter associated with antigen presenting (TAP) 1 and TAP2 genes are localized in the major histocompatability complex (MHC) class II region and form a heterodimer playing a key role in endogenous pathways for antigen presentation. Defects of these genes have been reported to be common in different types of cancer. Polymorphisms identified in these loci have also been investigated and repo...

Journal: :The Journal of biological chemistry 2006
Susanne Schrodt Joachim Koch Robert Tampé

The transporter associated with antigen processing (TAP) translocates antigenic peptides from the cytosol into the endoplasmic reticular lumen for subsequent loading onto major histocompatibility complex (MHC) class I molecules. These peptide-MHC complexes are inspected at the cell surface by cytotoxic T-lymphocytes. Assembly of the functional peptide transport and loading complex depends on in...

2012
Qing Ye Ke He Shao-Ying Wu Qiu-Hong Wan

The bacterial artificial chromosome (BAC) system is widely used in isolation of large genomic fragments of interest. Construction of a routine BAC library requires several months for picking clones and arraying BACs into superpools in order to employ 4D-PCR to screen positive BACs, which might be time-consuming and laborious. The major histocompatibility complex (MHC) is a cluster of genes invo...

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