Network pharmacology is becoming a cutting-edge research field in current drug discovery and drug development thanks to rapid progress in systems biology, network biology, and chemical biology. By integrating reductionist and systems approaches as well as computational and experimental methods, network pharmacology has great potential to act as the next generation mode of drug research. Network...

The long-term clinical practice of traditional Chinese medicine (TCM) confirms its importance and essential role in the health care system in China, especially in the prevention and treatment of chronic diseases [1]. TCM is not only looked upon as a bright pearl, but also a treasure house in Chinese ancient culture. TCM has made great contribution to the health of Chinese people for thousands o...

BACKGROUND Atopic dermatitis among children is an important issue due to relapses and skin manifestations. Traditional Chinese medicine (TCM) is commonly used to treat children with atopic dermatitis. The aim of this study was to investigate the characteristics and TCM prescriptions of patients with atopic dermatitis using a nationwide database. METHODS Children younger than 12 years of age d...

ETHNOPHARMACOLOGICAL RELEVANCE Osteoporosis is a chronic epidemic which can leads to enhanced bone fragility and consequent an increase in fracture risk. Traditional Chinese medicine (TCM) formulas have a long history of use in the prevention and treatment of osteoporosis. Antiosteoporotic TCM formulas have conspicuous advantage over single drugs. Systematic data mining of the existing antioste...

We present a TCM-Grid for Traditional Chinese Medicine (TCM). The purpose of the TCM-Grid is to aid the development of distributed systems that help health professionals, researchers, enterprizes and personal users to retrieve, integrate and share TCM information and knowledge from geographically decentralized TCM database resources and knowledge base resources in China. Our approach involves d...

Although natural medicines are generally considered to be safer than synthetic medicines, some reports on toxicity of many herb drugs, for example Traditional Chinese Medicine (TCM), attract more and more common public attention recently. The reasons for these cardiovascular toxic effects are not always satisfactory. Not all these clinical symptoms can be observed regularly. Cardiovascular toxi...

Coronary heart disease (CHD) is the leading cause of death. As the main treatment of CHD, modern medicine has improved dramatically in recent years. Although researches of TCM and integrative medicine on CHD are witnessed encouraging progress in many respects, the role TCM playing in the prevention and treatment of CHD has been unprecedentedly challenged under such circumstance of the very fast...

BACKGROUND Compare changes in types of hospital service revenues between traditional Chinese medicine (TCM) hospitals and Western-medicine based general hospitals. METHODS 97 TCM hospitals and 103 general hospitals were surveyed in years of 2000 and 2004. Six types of medical service revenue between the two types of hospitals were compared overtime. The national statistics from 1999 to 2008 w...

in recent years, some in the West have begun to recognize traditional chinese medicine (tcM) as a potential source of new drug candidates (corson & crews, 2007; Efferth et al, 2007; Li & zhang, 2008; Schmidt et al, 2007). at the same time, the practice of tcM in Western countries has been increasing (institute of Medicine, 2005). as tcM is usually thought to have evolved independently of Wester...

BACKGROUND This study aims to investigate community pharmacist's perception on the provision of over-the-counter (OTC) traditional Chinese medicine (TCM) pharmaceutical services; focusing on the areas of their attitude, general practice, perceived barriers and suggested improvements. METHODS Questionnaire survey targeting community pharmacists in Harbin of China was applied in this study. Que...