Disturbances of liver function tests are common in polymyalgia arteritica, but the underlying liver lesion has not been defined. We report a patient who was demonstrated to have a giant cell arteritis involving both the hepatic and temporal arteries, and we discuss the possibility that such an arteritis involving the hepatic arteries is responsible for the abnormalities of liver function seen i...

Giant cell arteritis (temporal arteritis; GCA) is a systemic vasculitis of medium and large arteries, affecting predominantly the aortic branches to the head and neck. Temporal arteritis was first described by Horton et al in 1932 and classically presents with a combination of polymyalgia rheumatica, headache, and manifestations of systemic illness (fever, anemia, anorexia, malaise, and weight ...

emporal arteritis and polymyalgia rheumatica, different T clinical manifestations of the same systemic granulomatous vasculitis, predominantly affect older persons.' Huston and colleagues estimated the prevalence to be 1 in 750 persons older than 50 years of age.' Temporal arteritis often requires high and sometimes sustained corticosteroid therapy to prevent the development of sight threatenin...

Ophthalmic involvement in giant cell arteritis can manifest in a number of ways. Central retinal artery occlusion is one of the common causes of visual loss in giant cell arteritis. On the contrary, branch retinal vein occlusion is rarely associated with the latter. We report an 89-year-old lady with acute left central retinal artery occlusion on a background of progressive decline in vision ov...

The work which has led to this report was undertaken in an attempt to improve the diagnostic accuracy and thereby the treatment of giant cell arteritis and polymyalgia rheumatica. Whether these conditions are the same, related, or quite different diseases is a well-known problem; detailed studies have provided support for all three possibilities (Gordon, Rennie, and Branwood, 1964; Hamrin, Jons...

OBJECTIVE To report the association of temporal arteritis and enhancement of the dura mater and temporalis muscle. DESIGN AND METHODS A single patient with a complaint of headache and diplopia was studied. SETTING Academic medical center. PATIENT A 69-year-old man presented with lateral rectus weakness, temporal artery tenderness, and an erythrocyte sedimentation rate of 65 mm/h. INTERV...

To explore the role of adhesion molecules in mediating mononuclear cell localisation, development of the granulomatous reaction, and cell mediated damage to the arterial wall in giant cell arteritis, 17 temporal artery biopsy specimens were examined. Eleven showed the histological features of giant cell arteritis and six showed no evidence of arteritis. All were examined for the expression of L...

Giant cell arteritis may occasionally affect the aorta and larger pulmonary arteries. This can be part of a systemic disease such as necrotising sarcoid granulomatosis or systemic lupus erythematosus, but may also be due to specific conditions, particularly disseminated temporal arteritis (giant cell arteritis). When the pulmonary arteries alone are affected they are usually medium sized and af...