A 69-year-old male previously diagnosed with acute myeloblastic leukemia secondary to myelodysplastic syndrome (LMA with dysplasia, karyotype 46XY, and no cytogenetics abnormalities) refractory to treatment (hydroxyurea, cytarabine, mitoxantrone, and azacitidine) presented with right-side otalgia, otorrhea, and deafness with 2 months progression. He had been treated with oral ciprofloxacin, ear...

Manasse was first reported cholesterol granuloma of the middle ear in 1917. Shambaugh in 1929 described idiopathoc hemotympanum as a cause to the development of cholesterol granuloma of middle ear. Cholesterol granuloma have been seen in multiple area of the human body where cholesterol crystals may exist such as the lungs, breasts, peritoneum, mediastinum, liver, spleen, thyroid, kidneys, lymp...

Myeloid sarcoma is a rare condition that's caused by the aggregation of immature myeloid cells in leukemic patients. Myeloid sarcoma occurring in the temporal bone more frequently involves the mastoid bone than is the case for metastatic lesions arising from non-systemic malignancies. The disease is difficult to diagnose when it presents with symptoms that mimic otomastoiditis. However, an earl...

Vestibular schwannoma (VS) usually present the widening of internal auditory canal (IAC), and these bony changes are typically limited to IAC, not extend to temporal bone. Temporal bone invasion by VS is extremely rare. We report 51-year-old man who revealed temporal bone destruction beyond IAC by unilateral VS. The bony destruction extended anteriorly to the carotid canal and inferiorly to the...

OBJECTIVES The authors recently demonstrated that extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone. The present objective was to investigate the expressions and the roles of epithelial-mesenchymal transition (EMT) in SCC of the temporal bone. STUDY DESIGN Retrospective patient file review and immunohistochemical study of tissue...

Introduction: Skull base and temporal bone fractures are frequently associated with severe high-velocity head trauma. Even though most of these fractures are not life-threatening, they are often associated with severe morbidity which has got a major impact on the quality of life. Conventional computed tomography (CT) has got its own limitations and often missed finer details of the temporal bon...

OBJECTIVE To compare the traditional system of radiographic classification of temporal bone fractures (transverse vs longitudinal vs oblique) with a newer system (otic capsule violating vs otic capsule sparing) with respect to their ability to predict sequelae of temporal bone trauma. DESIGN Retrospective chart and radiology review. SETTING University trauma center and Department of Otolary...

BACKGROUND Inverted papilloma involving the temporal bone is an extremely rare occurrence. Reports in the literature suggest a higher recurrence rate and association with squamous cell carcinoma in Schneiderian-type papillomas of the middle ear than in sinonasal Schneiderian-type papillomas. OBJECTIVES To investigate the expression of apoptosis-related proteins, markers of cell proliferation ...

Osteomas are slow growing bony tumors common in fronto-ethmoid regions and rare in temporal bone. These are usually asymptomatic and require treatment mainly for cosmetic reasons. We describe a case of temporal bone osteoma in a female.