this study was designed to explore the protective effects of abrus precatorius l. (leguminosae) (ap) in hepg2 cells and n-nitrosodiethylamine (ndea) induced hepatocellular carcinoma in swiss albino rats. the effects of aqueous/ethanolic (50%) extract of ap on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in ndea (200 mg/kg and ccl4, 3 m...

objective(s):cyclophosphamide (cp) toxicity on testis was hampered by squid ink polysaccharide (sip) via restoration of antioxidant ability in our previous investigations. this study investigated roles of nrf2/are signal pathway in testis of treated mice. materials and methods: male kunming mice were employed to undergo treatment with sip and/or cp. protein levels of nrf2, keap-1, histone deace...

abstract to assay the effect of acetylsalicylic acid pretreatment on enhancement of yield and yield components of barley (reihan-03) under water stress condition, an experiment was conducted as a spilt-plot arrangement based on randomized complete block design with four replications at the research field of shahid bahonar university of kerman, iran, in 2012-2013. irrigation condition was arrang...

common vetch ( vicia sativa l.) an annual forage, belonging to the fabaceae family is one of the highly cultivated forage legumes in iran. drought stress is a serious adverse factor that limits plant growth and productivity, inducing a range of physiological as well as biochemical responses in plants. it may also lead to generation of oxygen activated species which in turn result in cell destru...

aim: was to assess the effects of ramadan observance upon repeated sprints and associated inflammatory and oxidative stress responses. methods: ten young trained boxers were tested during a control period (c), at the end of the first week (r-1), and during the fourth week of ramadan observance (r-4). on each occasion, they performed three vertical jumps, 10 x 6 s repeated sprints on a cycle erg...

background: blood is permanently exposed to oxidation stress and therefore has a high antioxidants capacity. many different factors increasing the demand for the antioxidant capacity can be observed in the stored blood of donors. consequently, damage to erythrocytes by free radicals may occur. so it is useful to control the alternation of anti-oxidant enzymes in stored blood at different days o...

introduction throughout their life cycle, plants are subjected to various types of environmental stresses which include salinity, water deficit, temperature extremes, toxic metal ion concentration and uv radiation. these environmental factors limit the growth and productivity of plants to various degrees, depending upon severity of stress. heavy metal toxicity is one of the major current enviro...

Objective: Carob (Ceratonia siliqua L.) is an evergreen tree with fruits that have potent antioxidant activity. The aim of this study was to investigate alleviative effects of carob fruit hydro-alcoholic extract (CFHAE) against reproductive toxicity induced by lead (Pb) in male mice. Material and Methods: Forty-two NMRI adult male mice were randomly categorized into 7 groups (N=6). Group ...

Background: Cadmium is a potential pollutant of the environment. It manifests cyto-toxic effects in different organs in animals. In the testis, changes due to disruption of the blood-testis barrier and oxidative stress have been noted. Therefore, the present study was carried out to investigate the potential protective effects of vitamin E and green tea extract in combination against cadmium (C...

Study of the activities of hyaluronidase, lactate dehydrogenase isoenzyme-X and the dehydrogenases of sorbitol, alpha-glycerophosphate, glucose-6-phosphate, malate, glyceraldehyde-3-phosphate and isocitrate in the testes of mice of different ages showed that the changes were correlated with the stages of spermatogenic cell differentiation. The first 4 enzymes had activities which were low in ne...