This study aims to explore the ameliorative effects of L-glutamic acid (L-Glu) against carbon tetrachloride (CCl4) toxicity in male rats. Changes activities alanine and aspartate aminotransferases (ALAT, ASAT) were studied tissues blood Concentrations creatinine, triacylglycerol cholesterol also determined experimental animals. Intraperitoneal administration CCl4 rats led changes animals parame...

The biochemical mechanisms underlying the toxic effects of carbon tetrachloride on rat liver have been studied extensively (for references, see Recknagel, 1967; Slater, 1972). The earliest morphological disturbances described have concerned the endoplasmic reticulum; biochemical studies in vitro with microsomal fractions have emphasized the rapidity with which carbon tetrachloride damages many ...

chemical processes involved in cellular damage and regeneration are of importance in neo plasia. Agents such as carbon tetrachloride pro duce a sequence of liver damage, regeneration, and hepatoma formation. A single feeding of carbon tetrachloride produces extensive liver necrosis in mice, followed by a rapid proliferation of the re maining uninjured cells, until a normal cornple ment of funct...

Lupeol (1), epilupeol (2) and β-sitosterol (3) were isolated from the n-hexane and the carbon tetrachloride soluble fraction of a methanol extract of the leaves of Phoenix paludosa Roxb. The n-hexane, carbon tetrachloride and chloroform soluble materials from the concentrated methanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates...

Pseudomonas sp. strain KC (= ATCC 55595 = DSM 7136) is a denitrifying aquifer isolate that produces and secretes pyridine-2,6-bis(thiocarboxylate) (PDTC), a chelating agent that fortuitously transforms carbon tetrachloride without producing chloroform. Although KC has been used successfully for full-scale bioremediation of carbon tetrachloride, its taxonomy has proven difficult to resolve, as i...