BACKGROUND Thalamic dysfunction has been found in patients with posttraumatic stress disorder (PTSD), suggesting that the thalamus may be implicated in the etiology of PTSD. However, no studies have explored the functional connectivity between the thalamus and other brain regions during resting-state. The objective of the present study was to investigate the resting-state functional connectivit...

The thalamus is globally connected with distributed cortical regions, yet the functional significance of this extensive thalamocortical connectivity remains largely unknown. By performing graph-theoretic analyses on thalamocortical functional connectivity data collected from human participants, we found that most thalamic subdivisions display network properties that are capable of integrating m...

Although both sensory and motor signals in multiple cortical areas are modulated by eye position, the origin of eye position signals for cortical neurons remains uncertain. One likely source is the central thalamus, which contains neurons sensitive to eye position. Because the central thalamus receives inputs from the brainstem, these neurons may transmit eye position signals arising from the n...

OBJECTIVE The thalamus and cerebral cortex are connected via topographically organized, reciprocal connections. Previous studies have revealed thalamic abnormalities in schizophrenia; however, it is not known whether thalamocortical networks are differentially affected in the disorder. To explore this possibility, the authors examined functional connectivity in intrinsic low-frequency blood-oxy...

Central thalamus plays a critical role in forebrain arousal and organized behavior. However, network-level mechanisms that link its activity to brain state remain enigmatic. Here, we combined optogenetics, fMRI, electrophysiology, and video-EEG monitoring to characterize the central thalamus-driven global brain networks responsible for switching brain state. 40 and 100 Hz stimulations of centra...

The thalamus is thought to relay peripheral sensory information to the somatosensory cortex in the parietal lobe. Long-range thalamo-parietal interactions play an important role in inducing the effect of anesthetic. However, whether these interaction changes vary with different levels of anesthesia is not known. In the present study, we investigated the influence of different levels of isoflura...

Disclosure. The authors declare no conflicting interests, and this study was not supported or funded by any drug company. T he thalamus is the connection center of the brain. All synaptic impulses except olfactory are formed in the thalamus. Its current significance is its designation as the source of some diseases. Recent research shows that the thalamus has a critical role in schizophrenia 1 ...

The thalamus is a twinned bulb-shaped structures that form at the top of the brainstem on either side of the third ventricle. The thalamic complex is located in the posterior forebrain and includes the prethalamus and thalamus (formerly known as ventral thalamus and dorsal thalamus, respectively). This complex is the major sensory relay station of the brain, receiving all inputs (except olfacti...