We show that if all γ-ray bursts emit X-rays in a way similar to those observed by BeppoSax, much of the extinction along the line of sight in the host galaxy of the burst can be destroyed. Two mechanisms are principally responsible for dust destruction: grain heating and grain charging. The latter, which can lead to electrostatic stresses greater than the tensile strength of the grains, is oft...

We report on the mechanism of burst generation by populations of intrinsically spiking neurons, when a certain threshold in coupling strength is exceeded. These ensembles synchronize at relatively low coupling strength and lose synchronization at stronger coupling via spatiotemporal intermittency. The latter transition triggers fast repetitive spiking, which results in synchronized bursting. We...

Objective(s) Theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. It is used both as a prophylactic drug and to prevent acute exacerbations of asthma. The aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. Materials and Me...

Human studies suggest that cardiovascular neural sympathetic control is predominantly modulated by the right cerebral hemisphere. It is unknown whether post-ganglionic sympathetic activity [muscle sympathetic nerve activity (MSNA)] shows any functional asymmetry. Eight right-handed volunteers (3 women and 5 men, 32 +/- 2 yr of age) underwent ECG, beat-by-beat blood pressure, respiratory activit...

Differentiated Services (Diffserv) which was proposed by Internet Engineering Task Force (IETF), is a scalable and robust model for providing the end-to-end QoS. In the Diffserv networks, metering mechanisms are used to measure traffic stream. The single rate Three Color Meter (srTCM) [1],which was proposed by IETF,‏ meters an IP packet stream and marks its packets either green, yellow, or red....

The hippocampus is essential for episodic memory, which requires single-trial learning. Although long-term potentiation (LTP) of synaptic strength is a candidate mechanism for learning, it is typically induced by using repeated synaptic activation to produce precisely timed, high-frequency, or rhythmic firing. Here we show that hippocampal synapses potentiate robustly in response to strong acti...

CT ED P RO O Abstract When stimulated, vasopressin neurones discharge lengthy, repeating bursts of action potentials. An increase in the stimulus strength causes both a lengthening of the bursts’ active phase and an increase in the intra-burst firing frequency. Here we extend our earlier model (P. Roper, J. Callaway, W. Armstrong. J. Neurosci. 24(20) (2004) 4831.) for phasic bursting at a const...

objective: the purpose of this study was to investigate the role of fast inactivating (ia) voltage dependent potassium channels in shaping the discharge activity of cerebellar purkinje cells (pcs) in ataxic rats. materials and methods: male sprauge-dawley rats (40-60 g) were used in this study. ataxia was induced via single i.p. injection of 3-acethylpyridine (65 mg/kg). four days following ind...

We studied the effect of synaptic inputs of different amplitude and duration on neural oscillators by simulating synaptic conductance pulses in a bursting conductance-based pacemaker model and by injecting artificial synaptic conductance pulses into pyloric pacemaker neurons of the lobster stomatogastric ganglion using the dynamic clamp. In the model and the biological neuron, the change in bur...