نتایج جستجو برای: therapeutics
تعداد نتایج: 28507 فیلتر نتایج به سال:
+*Livingston, T (E-Osiris Therapeutics, Incorporated); *Kadiyala, S (E-Osiris Therapeutics, Incorporated); *ElKalay, M (E-Osiris Therapeutics, Incorporated); *Young, R (E-Osiris Therapeutics, Incorporated); *Kraus, K (E-Osiris Therapeutics, Incorporated); *Gordon, S (E-Osiris Therapeutics, Incorporated); *Peter, S (EOsiris Therapeutics, Incorporated) +*Osiris Therapeutics, Incorporated, Baltimo...
As ribonucleic acid (RNA) nanotechnology has advanced, it has been applied widely in RNA-based therapeutics. Among the range of approaches, enzymatically synthesized RNA structures for inducing RNA interference in cancer cells have potential for silencing genes in a target-specific manner. On the other hand, the efficiency of gene silencing needs to be improved to utilize the RNA-based system f...
When a cell is exposed to double-stranded RNA (dsRNA), mRNA from the homologous gene is selectively degraded by a process called RNA interference (RNAi). Here, we provide evidence that dsRNA is amplified in Caenorhabditis elegans to ensure a robust RNAi response. Our data suggest a model in which mRNA targeted by RNAi functions as a template for 5' to 3' synthesis of new dsRNA (termed transitiv...
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