PURPOSE To evaluate the influence of co-administered vehicles on in vitro dissolution in simulated gastric fluid of crushed immediate release tablets as an indicator for potential drug bioavailability compromise. METHODS Release and dissolution of crushed amlodipine, atenolol, carbamazepine and warfarin tablets were tested with six foods and drinks that are frequently used in the clinical set...

Microorganisms such as sperm routinely swim close to solid boundaries and within nonNewtonian fluids. In this paper, we exploit the lubrication approximation to model the motion of a flexible sheet near a rigid wall and immersed in a complex fluid. This allows us to specify an internally generated force density on the sheet and allow its shape and velocity to be determined by the interplay betw...

Experience in manufacturing MR fluids for commercial application has shown that some of the greatest barriers to commercial success are not factors or conditions normally considered in the laboratory. The present paper looks at conditions found in MR fluid devices operating in real-world applications where shear rates may exceed 10 5 sec and devices are called upon to operate for very long peri...

Abstract The problems of degradation on oil production can be solved by chemical EOR (Enchanced Oil Recovery) methods, polymer injection is the one kind methods. When fluids injected in to reservoir then it will increase sweep efficiency and fixed mobility ratio fluids. sample that tested this experiments biopolymer. Besides xanthan gum extracted using bacterial, side plant contained a compound...

• Reliable drag model identification: shear-thinning, -thickening, Newtonian fluids. Investigation of temporal phenomena (periodic shape fluctuations). Higher indexes (K, n) mean more sphericity and slow movement in linear path. Model extension for predicting small bubble rise low-viscosity liquids. A study the effects fluid type (shear-thinning, Newtonian, shear-thickening) periodic fluctuatio...

The classical viscous theory is limited to illustrating the characteristics of several materials like pseudoplastic and dilatant fluids. Sutterby fluid has features shear thinning thickening fluids because its Power law index. Therefore, this study considered an incompressible, time-independent electrically conducting flow across a rotating stretchable disk. disk experiences effect porous space...

The mechanical stability of the culms of monocotyledonous bamboos is highly attributed to the proper embedding of the stiff fibre caps of the vascular bundles into the soft parenchymatous matrix. Owing to lack of a vascular cambium, bamboos show no secondary thickening growth that impedes geometrical adaptations to mechanical loads and increases the necessity of structural optimization at the m...

Dispersing small particles in a liquid can produce surprising behaviors when the solids fraction becomes large: rapid shearing drives these systems out of equilibrium and lead to dramatic increases viscosity (shear-thickening) or even solidification (shear jamming). These phenomena occur above characteristic onset stress are forced into frictional contact. Here we show via simulations how this ...