Bivalent metal complexes having the composition M(Phen)Cl2 (where, M = Cu(II), Ni(II) and Co(II); Phen 1,10-Phenonthroline) are reacted with 2-acetylthiophene-4-phenyl-3-thiosemicarbazone (ATPT) to produce ternary molecular formula [M(Phen)(ATPT)Cl2] H2O. The characterized using physical (molar conductivity) spectral (mass spectra, infrared electronic spectroscopies) methods. Electrochemical be...

      In the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. Among the ligands tested, diacetyl-bis(N4-methylthiosemicarbazones) (ATSM) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde Bis(N4-methyl)thiosemicarbazone (P...

The minimal inhibitory concentrations of various antibiotics for a strain of Streptococcus pyogenes and a stable L-form of it were determined. These results were evaluated with those of other investigators similarly performed with S. faecalis and derived protoplasts. Differences in reaction to puromycin, bacitracin and ristocetin were apparent only between the wall-less derivatives. The polyene...

Two oxovanadium(IV) complexes of [VO(msatsc)(phen)], (1) (msatsc = methoxylsalicylaldehyde thiosemicarbazone, phen = phenanthroline) and its novel derivative [VO (4-chlorosatsc)(phen)], (2) (4-chlorosatsc = 4-chlorosalicylaldehyde thiosemicarbazone), have been synthesized and characterized by elemental analysis, IR, ES-MS, (1)H NMR, and magnetic susceptibility measurements. Their antitumor effe...

The chelating behavior of the thiosemicarbazone derivatives of 2-hydroxy-8-R-tricyclo[7.3.1.0.(2,7)]tridecane-13-one (where R = H, CH3, C6H5) towards Co(II), Ni(II) and Cu(II) has been investigated by elemental analysis, molar conductivity measurements, UV-VIS, IR, ESR spectroscopy and thermal studies. It was deduced from the experiments performed that the ligands coordinate to metal ions in di...

in present studies the synthesis, characterization and biological properties ofoxovanadium(iv) coordination compounds of 4[n-(4′-ethylbenzalidene)amino] antipyrinethiosemicarbazone (ebaapts) and 4[n-(2′,4′-dimethylbenzalidene)amino] antipyrinethiosemicarbazone (dmbaapts) with the general composition vox2l (x = c1-, br-, i-, no3-or ncs-) and vo(cio4)2(l)h2o (l = ebaapts or dmbaapts) are describe...

The efficacy of 1-methylisatin 3-thiosemicarbazone for the inhibition of neurovaccinia virus in mice has been documented by D. J. Bauer and P. W. Sadler (Brit. J. Pharmacol. 15:101, 1960). The inhibition of adenovirus multiplication by this compound has been reported by D. J. Bauer and K. Apostolov (Science 154:796, 1966). The present communication pertains to the microbial conversion of 1-meth...