نتایج جستجو برای: thymic hyperplasia
تعداد نتایج: 50246 فیلتر نتایج به سال:
The competence of cellular immunity depends on a diverse T-cell receptor (TCR) repertoire arising from thymic output. Normal thymopoiesis arises from marrow-derived CD3(-)CD4(-)CD8(-) triple-negative T-cell progenitors (TN), which develop into mature single-positive (SP) CD4 or CD8 T cells after expressing both CD4 and CD8 (double-positive, DP) transiently, leading to de novo T-cell production....
OBJECTIVE Single fibre electromyography (SFEMG) and repetitive nerve stimulation (RNS) are routinely performed investigations in evaluation of patients with myasthenia gravis (MG). Significant number of MG patients have a thymic pathology. We aimed to explore the relationship between the SFEMG and RNS findings with the presence of thymic pathology. METHODS We studied 159 consecutive patients ...
Cervical thymic cyst is a rare entity of either congenital or inflammatory origin described infrequently in literature. The asymptomatic nature of the entity and the rarity of the lesion frequently lead to a diagnostic dilemma many times. We present a case of cervical thymic cyst that presented to us as an asymptomatic neck mass that was managed surgically. Cervical thymic cyst should be kept a...
Abnormal overexpression of CXCL13 is observed in many inflamed tissues and in particular in autoimmune diseases. Myasthenia gravis (MG) is a neuromuscular disease mainly mediated by anti-acetylcholine receptor autoantibodies. Thymic hyperplasia characterized by ectopic germinal centers (GCs) is a common feature in MG and is correlated with high levels of anti-AChR antibodies. We previously show...
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