نتایج جستجو برای: tissue transglutaminase antibodies
تعداد نتایج: 1049097 فیلتر نتایج به سال:
Dermatitis herpetiformis and coeliac disease are gluten sensitive diseases, which have common immunopathological and genetic mechanisms. Neuropsychiatric complications have been reported in up to 26% of patients with coeliac disease. This is probably an overestimate, because of the chance associations with some common neurological conditions such as epilepsy. The pathogenesis is speculative but...
AIMS To determine coeliac disease prevalence by an anti-transglutaminase antibody assay in a large paediatric population; to evaluate acceptance of the screening programme, dietary compliance, and long term health effects. METHODS Cross-sectional survey of 3188 schoolchildren (aged 6-12) and prospective follow up of diagnosed cases. Main outcome measures were: prevalence of coeliac disease de...
BACKGROUND Coeliac disease is one of the commonest underdiagnosed diseases in general practice. The autoantigen recognised by the sera of patients with coeliac disease has recently been identified as tissue transglutaminase. AIMS We evaluated a simple non-invasive immunological dot blot assay for coeliac disease, suitable for use by the general physician in the ambulatory setting. The sensiti...
BACKGROUND Patients diagnosed with irritable bowel syndrome may have coeliac disease. AIM To evaluate the cost-effectiveness of coeliac disease testing in suspected irritable bowel syndrome. METHODS We used decision analysis to estimate the number of coeliac disease cases detected, quality-adjusted life-years gained, and costs resulting from testing suspected irritable bowel syndrome patien...
The levels and activity of tissue transglutaminase were studied in human peripheral blood monocytes during differentiation into macrophages in vitro. The enzyme was present at low levels in freshly isolated monocytes (less than 20 ng/mg cell protein) but increased 50-fold during 10 d of adherent culture in autologous serum, reaching levels of 0.1% of total cellular protein. The rate of appearan...
Background: Celiac disease (CD) is an autoimmune affecting the small intestine, triggered by gluten. The pathogenesis of CD has been well defined, and increasing prevalence this had led to studying several environmental risk factors that may trigger process in intestine. Infection one most important can processes. researchers have studied association between H. pylori infection CD, authors repo...
Methods Descriptive analysis of a cohort of Italian patients with PANDAS.Between may 2009 may 2013 we observed 65 pts (50 M, 15 F, mean age: 100.8 ± 32,9 months) with OCD and/or tics starting before puberty, associated with a previous GAS infection. Demographic and familiar data, routine and specific laboratory data: thyroid function, autoimmunity tests (ANA, anti-dsDNA, antiENA, anti-cardiolip...
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