نتایج جستجو برای: tnfaip3
تعداد نتایج: 403 فیلتر نتایج به سال:
The most consistent finding derived from the WTCCC GWAS for rheumatoid arthritis (RA) was association to a SNP at 6q23. We performed a fine-mapping of the region in order to search the 6q23 region for additional disease variants. 3962 RA patients and 3531 healthy controls were included in the study. We found 18 SNPs associated with RA. The SNP showing the strongest association was rs6920220 [P ...
1Institute for Cancer Genetics, Departments of Pathology and Genetics & Development, and the Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY; 2Laboratory of Experimental Oncology and Lymphoma Unit, Oncology Institute of Southern Switzerland (IOSI), Bellinzona, Switzerland; 3Istituto Dalle Molle di Studi sull’Intelligenza Artificiale, Manno, Switzerland; and 4Divisi...
Abstract We have developed an innate immune model of colitis that occurs in the absence adaptive immunity, is early-onset, 100% penetrant, chronic, and dependent on microbes. villin-TNFAIP3 transgenic mice, crossed to RAG1-/- mice (aka TRAG mice) develop immune-mediated not observed or littermates. Antibiotic treatment prevents mice. Thus, we sought investigate microbes drive chronic immunity. ...
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