Studies have shown an association between oxidative stress and alopecia. Patients with alopecia generally exhibit lower levels of antioxidants in their scalp area as well as a higher lipid peroxidation index. Tocotrienols belong to the vitamin E family and are known to be potent antioxidants. Hence, a study was conducted to investigate the effect of tocotrienol supplementation on hair growth in...

Palm oil contains vitamin E which comprises two structurally similar compounds namely tocopherols and tocotrienols. For many years considered the best therapy in curing disease, but recent research advances, tocotrienol has been widely used as a powerful several diseases, including cancer. We prepared this article to review analyze role of tocotrienols from palm anticancer molecules their mecha...

Tocotrienols exhibit anti-inflammatory properties over macrophages and promote cytotoxicity in activated pancreatic stellate cells, suggesting that they may limit chronic pancreatitis progression. We aimed to quantitate the effect of oral tocotrienols on a rat model of chronic pancreatic injury. Chronic-like pancreatitis was induced by repeated arginine pancreatitis. Palm oil tocotrienol-rich f...

BACKGROUND Tocotrienols, lipid-soluble antioxidants with vitamin E activity, have been reported to lower LDL-cholesterol concentrations and platelet aggregation in men, but results are contradictory. OBJECTIVE To examine in detail the effects of a vitamin E concentrate rich in tocotrienols on serum lipoproteins and on platelet function in men at risk for cardiovascular disease. DESIGN In th...

A tocotrienol-rich fraction (TRF(25)) and novel tocotrienols (d-P(21)-T3 and d-P(25)-T3) of rice bran significantly lowered serum and low density lipoprotein cholesterol levels in chickens. The present study evaluated the effects of novel tocotrienols on lipid metabolism in swine expressing hereditary hypercholesterolemia. Fifteen 4-mo-old genetically hypercholesterolemic swine were divided int...

The “vitamin E” family consists primarily of four naturally occurring tocopherols (alpha-, beta-, gammaand delta-) and four unsaturated corresponding tocotrienols, which differ in their structure by the composition of methyl groups attached to the chromanol ring. Apart from their potent antioxidant activity, it is hypothesized that some of these compounds might play protective role against canc...