The presence of neck metastasis was the most important prognostic factor in head and neck cancer [1,2], successful management of neck disease was considered one of the most important aspects of treatment. However, huge controversy existed regarding the treatment of the neck in patients with cT1-2N0 tongue cancer [3-6]. In this study, we aimed to evaluate the role of Selective Neck Dissection (S...

BACKGROUND Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer diagnosed within the oral cavity worldwide. Many studies in India report OTSCC ranking among the top two most common subsites within the oral cavity. India is often labeled the oral cancer capital of the world. The incidence of tongue cancers in the population-based cancer registry (PBCR) of Chennai is showing an i...

Introduction: Individual oral stent is a mouth-opening device that used in head and neck cancer radiotherapy with the intention of decreasing radiation dose to health tissues. The aim of this study was to check the dose delivered to both the hard palate and tongue when patient uses the stent during radiotherapy of tongue carcinoma. Methods and materials<stron...

OBJECTIVE To assess the feasibility of optical imaging using activatable near-infrared fluorescence (NIRF) agents to detect oral cancer and cervical lymph node metastasis in vivo. DESIGN In vivo study. SETTING University medical center. SUBJECTS Female nude mice aged 4 to 6 weeks. INTERVENTION Luciferase-expressing OSC-19-luc cells were injected into the tongues of nude mice. A control ...

Oral cancers are the 11th most common malignancy reported worldwide, accounting for 3% of all newly diagnosed cancer cases, and one with high mortality ratios among all malignancies. The objective of this study was to study the electrical properties of cancerous tongue tissue (CTT) and normal tongue tissue (NTT). Five tongue cancer patients participated in this study. A disposable probe incorpo...

Tongue cancer is one of the most common malignancies all oral malignancies. Cancer staging induced by a systemic inflammatory response with markers, them neutrophil-lymphocyte ratio (NLR). This study aims to provide an overview NLR as marker degree inflammation in patients tongue cancer. systematic literature review was conducted online from January 2021 March against articles reporting RNL act...

Several E3 ubiquitin ligases have been confirmed that they are related to the tumorigenesis. This study aims to find the tongue cancer-related E3 ubiquitin ligase. The E3 ubiquitin ligase library was screened. The effect of candidate molecule on tongue cancer was validated through cell viability, cell proliferation, colony formation, invasive assay in vitro, and the xenograft model in vivo. The...