Traditional views of visual processing suggest that early visual neurons are static spatiotemporal filters that extract local features by feedforward computation. The extracted information is then fed forward through a chain of modules to successively higher visual areas for further analysis. Recording from early visual neurons in awake behaving monkeys, we revealed there are many levels of com...

use of nano-materials has increased in various aspects of human life. however, possible outbreak of nano-materials toxicity in humans and other organisms is one of the future challenges. different chemical precursors which are used in chemical approaches for production of nano-materials may have secondary and sometimes toxic effects in living organisms. these secondary effects may be reduced in...

Introduction: Recent findings suggest deaf children with cochlear implants (CIs) do not use sentence context to help perceive spoken words (Conway et al., 2014). This indicates that children with CIs may understand language primarily using bottomup processes, recognizing words separately and failing to integrate them to formulate meaning for the entire sentence. However, typical-hearing (TH) ch...

All sound separation systems based on perception assume a bottom-up or Marr-like view of the world. Sound is processed by a cochlear model, passed to an analysis system, grouped into objects, and then passed to higher level processing systems. The information flow is strictly bottom up, with no information flowing down from higher level expectations. Is this the right approach? This paper summa...

Dehaene, Changeux, Naccache, Sackur, and Sergent (2006) and Koch and Tsuchiya (2007) recently proposed taxonomies that distinguish between four processing states, based on bottom-up stimulus strength and top-down attentional amplification. The aim of the present study was to empirically test these processing states using the priming paradigm. Our results showed that attention (prime attended or...

Both the top-down and bottom-up processing are identified in language comprehension: the top-down processing depends on previous language experience and the bottom-up processing depends on instant language inputs. In speech perception, both types of processing are needed while perceiving pitch variations as lexical tones. In this paper, based on three ERP experiments, we propose a temporal mode...

Top-down and bottom-up mass spectrometry methods can generate gas phase fragments and use these to identify proteins. Top-down methods, in addition, can provide the mass of the protein itself and therefore additional structural information. Despite the conceptual advantage of top-down methods, the market share advantage belongs to bottom-up methods as a result of their more robust sample prepar...