The role of various parathyroid hormone (PTH) radio-immunoassays in the diagnosis of primary hyperparathyroidism (PHP) is controversial. A series of 204 patients with surgically proven PHP was studied. Serum total calcium, serum ionized calcium, amino (N)-terminal PTH and carboxyl(C)-terminal PTH were assessed in relation to the volume and weight of adenomatous or hyperplastic parathyroid tissu...

The objective was to investigate the hypothesis that environmental exposure to cadmium may affect calcium metabolism in the population at large. The 1987 participants (965 men and 1022 women), from 20 to 80 years old, constituted a random sample of the population of four Belgian districts. The urinary excretion of cadmium, a measure of lifetime exposure, averaged 9.3 nmol/24 h in men (range 0.4...

Total and corrected (for albumin) serum calcium levels were investigated in a cross-sectional study of 394 patients with rheumatoid arthritis, 4490 healthy subjects, and 2609 inpatients at a district general hospital. Patients with rheumatoid arthritis had lower mean calcium levels than the healthy subject (p less than 0.001), but had similar levels to inpatients at the district general hospita...

BACKGROUND Left ventricular hypertrophy (LVH) is prevalent in patients with type 2 diabetes mellitus (T2DM). Recent studies show that an increase in albumin-adjusted serum calcium level is associated with an elevated risk of T2DM. We speculate that increased serum calcium levels in T2DM patients are related to LVH prevalence. METHODS In this echocardiographic study, 833 normocalcemia and norm...

ORIGINAL ARTICLE Bangladesh J Med Biochem 2010; 3(2): 57-60 premature delivery. In the developing countries, preeclampsia affects 4.4 percent of all deliveries and may be as high as 18 percent in some settings in Africa4. Development of a simple and reliable biochemical test is, therefore, important to detect pregnant women in the early stage of preeclampsia. Several biochemical changes occur d...

BACKGROUND Ionized calcium (iCa) is measured frequently in hospitalized patients, and hypocalcemia is frequently found, seemingly supporting the practice. METHODS We retrieved the results of 58 040 iCa tests and records of intravenous (IV) and oral calcium supplementation from laboratory and hospital information systems and evaluated them for frequency of testing, frequency of hypocalcemia, a...

The effects of anionic salts in the transition diet on serum and urine calcium at calving and on peripartal health, subsequent milk production and fertility performance were studied in a well-managed, high-producing Friesland dairy herd. Over a period of a year, approximately 21 days before the expected date of calving, 28 pre-partum heifers and 44 multiparous dry cows were randomly allocated w...

The cause or causes of hypercalcemia and hypercalcuria in sarcoidosis are obscure. Harrell and Fisher (1) were the first to emphasize that hypercalcemia, hyperproteinemia and elevated serum alkaline phosphatase could occur in this disease. Dent etat (2) believed that bone destruction represented the cause of hypercalcemia. Anderson et at (3) concluded from their studies that increased calcium a...

THE study of the diffusibility of blood serum-calcium has been an interesting development in the investigation of calcium metabolism. The finding of Rona and Takahashi [1911], that only a part of the serum-calcium was diffusible through membranes impermeable to protein, has been corroborated by many observers and by various methods. The figures for diffusibility recorded in the literature cover...