Trichoepitheliomas are epidermal appendageal hamartomas, which usually present as solitary lesions; rarely multiple lesions may be present, mainly involving the centrofacial skin symmetrically. We report herein an adolescent male patient with multiple trichoepitheliomas, linearly arranged and dermatomal, present since birth, along the left side of the neck.

Sir—The report of unexplained deaths associated with thalidomide therapy for toxic epidermal necrolysis by Pierre Wolkenstein and colleagues (Nov 14, p 1586), points to the need for a more complete understanding of the putative mechanism(s) of action of this drug. This issue is lent further urgency by the recent licensure of thalidomide by the US Food and Drug Administration for the treatment o...

Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a widespread life-threatening mucocutaneous disease where there is extensive detachment of the skin and mucous membrane. Many factors involved in the etiology of TEN including adverse drug reactions. Here we are reporting a case of toxic epidermal necrolysis in an adult male patient after receiving carbamazepine in a 38 year o...