Surgical Treatment. -By Israel Bram, m.d. C. V. Mosby Company, St. Louis, 1920. Thk author should entertain no fear that his book may not be tolerated: it rather requires a welcome. The whole subject of Graves' disease is carefully reviewed: no new theories of its pathogenesis are advanced, but the author inclines to the view that the hyperthyroidism of the disease is itself an incidental produ...

We report a case of amiodarone induced toxic goitre, presenting with thoracic inlet obstruction which required surgical intervention. Though thyrotoxicosis caused by amiodarone is recognised, to our knowledge thoracic inlet compression has not been previously described.

Thyroid storm or thyroid crisis is an acute, life-threatening exacerbation and sudden releasing large amounts of thyroid hormone in a short period of time. Only 1%–2% of people with hyperthyroidism will develop thyroid storm[1]. Thyroidectomy was formerly the most common cause of thyroid crisis. Nowadays post thyroidectomy crisis is an uncommon incidence, because of preoperative testing and ear...

OBJECTIVES To evaluate procalcitonin (PCT) utility as a marker of medullary thyroid cancer (MTC). MATERIAL AND METHODS Calcitonin (CT) and PCT levels were measured in MTC patients and patients with serious bacterial infections. 70 patients were enrolled in the study: 6 MTC active patients: 4 with disseminated, unreoperable disease and 2 re-operated patients, in whom markers were checked befor...

The use of thyroid-depressant agents in the control of hyperthyroidism has raised questions concerning their relationship to other goitrogens and their mode of action. Other problems have been encountered as well, particularly with respect to toxic reactions, the effect of preliminary iodine administraton, and the control of the hypothyroid state which may result. The information available on t...

INTRODUCTION The therapeutic effect of radioactive iodine ((131)I) on benign goitre consists of the emission of tissue-destructive beta-radiation. Since the range of beta (131)I radiation in tissue can reach 2.4 mm, it can affect the adjacent parathyroid glands. The purpose of this paper is to assess parathyroid function in patients with toxic and non-toxic goitres, up to five years following (...

Patients with large benign goiters often present local compressive symptoms that require surgical treatment, including dysphagia, neck tightness, and airway obstruction. In contrast, patients with such goiters who remain asymptomatic may be observed after exclusion of malignancy. The use of levothyroxine (LT4) to reduce the volume of the goiter is still a controversial treatment for large goite...