The Trusted Platform Module TPM is a basic but nevertheless very complex security component that can provide the foundations and the root of security for a variety of applications. In contrast to the TPM, other basic security mechanisms like cryptographic algorithms or security protocols have frequently been subject to thorough security analysis and formal verification. This paper presents a fi...

Studies of the efficacy of topiramate (TPM) in infants and young children are few. Here we report an open, prospective, and pragmatic study of effectiveness of TPM in terms of epilepsy syndromes, in children aged less than 2 years. The median follow-up period was 11 months. We enrolled 59 children in the study: 22 affected by localization-related epilepsy (LRE), 23 by generalized epilepsy, six ...

Ischemic heart disease (IHD) has been linked to exposures to airborne particles with an aerodynamic diameter <2.5 μm (PM2.5) in the ambient environment and in occupational settings. Routine industrial exposure monitoring, however, has traditionally focused on total particulate matter (TPM). To assess potential benefits of PM2.5 monitoring, we compared the exposure-response relationships between...

In the literature of Total Productive Maintenance (TPM), a large number of frameworks have been proposed by different authors and consultants. If an organisation or a maintenance manager has to make a strategic decision of implementing TPM, it may not be easy for them to identify a suitable framework from a plethora of frameworks that are available in literature. Hence, in this paper, an attemp...

To gain more confidence in our understanding of the apparatus and analysis, we compared our experimental calibration curve to one we generated from a mathematical model of the system, following [1, 2]. The root-mean-square excursion of the projected bead location away from its tether point is controlled by various competing effects: (i) In the absence of any bead or wall, the chain’s endpoint w...

PURPOSE To explore the feasibility, safety and efficacy of enterally administered topiramate (TPM) as an adjunctive treatment for adult patients with refractory generalized convulsive status epilepticus (RGCSE). METHODS This prospective open-label non-randomized clinical trial was performed at Namazee hospital, Shiraz University of Medical Sciences, Shiraz, Iran from January 2013 through Febr...

We conducted an open, add-on study with topiramate (TPM) as adjunctive therapy in Lennox-Gastaut syndrome (LGS), to assess the long-term efficacy and safety and to evaluate quality of life (QL) measurements in the chronic use of TPM. We studied 19 patients (11 male; age ranging from 4 to 14 years) with uncontrolled seizures receiving 2-3 anti-epileptic drugs. Patients were followed up to 36 mon...

In order to better understand the training and athletic activity of horses, we must have complete understanding of the isoform diversity of various myofibrillar protein genes like tropomyosin. Tropomyosin (TPM), a coiled-coil dimeric protein, is a component of thin filament in striated muscles. In mammals, four TPM genes (TPM1, TPM2, TPM3, and TPM4) generate a multitude of TPM isoforms via alte...

We show that Topiramate (TPM) treatment normalizes whole body insulin sensitivity in high-fat diet (HFD)-fed male Wistar rats. Thus drug treatment markedly lowered glucose and insulin levels during glucose tolerance tests and caused increased insulin sensitization in adipose and muscle tissues as assessed by euglycemic clamp studies. The insulin-stimulated glucose disposal rate increased twofol...

The Trusted Platform Module (TPM) is a hardware chip designed to enable computers to achieve greater security. Proof of possession of authorisation values known as authdata is required by user processes in order to use TPM keys. If a group of users are to be authorised to use a key, then the authdata for the key may be shared among them. We show that sharing authdata between users allows a TPM ...