نتایج جستجو برای: transglutaminases

تعداد نتایج: 1752  

2009
Uno Tagami Nobuhisa Shimba Mina Nakamura Kei-ichi Yokoyama Ei-ichiro Suzuki Takatsugu Hirokawa

Transglutaminases (TGases) are used in fields such as food and pharmaceuticals. Unlike other TGases, microbial transglutaminase (MTG) activity is Ca(2+)-independent, broadening its application. Here, a three-dimensional docking model of MTG binding to a peptide substrate, CBZ-Gln-Gly, was simulated. The data reveal CBZ-Gln-Gly to be stretched along the MTG active site cleft with hydrophobic and...

2008
Sonia Quaratino Mariano Cimmino Olivier N. Cexus Marco Londei Valeria R. Villella Maria D'Apolito Luigi Maiuri Alessandro Luciani Ida Giardino Valeria Raia Maria D’Apolito Massimo Pettoello-Mantovani Stefano Guido Carolina Ciacci

Journal: :Chemical communications 2010
Hiroki Abe Masahiro Goto Noriho Kamiya

A small glutamine donor substrate was designed for single-step and site-specific protein multifunctionalization catalyzed by microbial transglutaminase.

2013
Huilin Yang Tiansheng He Wenxia Wu Weitao Zhu Bai Lu Wanju Sun

Here, we report the draft annotated genome sequence of Streptomyces mobaraensis strain DSM 40847, which is used in industry to produce microbial transglutaminase. The genome sequence will allow for the characterization of the molecular mechanisms underlying the beneficial properties of this organism.

Journal: :Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2009
L Elli C M Bergamini M T Bardella D Schuppan

Transglutaminases are a family of eight currently known calcium-dependent enzymes that catalyze the cross-linking or deamidation of proteins. They are involved in important biological processes such as wound healing, tissue repair, fibrogenesis, apoptosis, inflammation and cell-cycle control. Therefore, they play important roles in the pathomechanisms of autoimmune, inflammatory and degenerativ...

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