The association between phenacetin abuse and renal papillary necrosis is widely known. Recently, reports in the European literature indicated a possible correlation between phenacetin abuse and the development of transitional cell carcinoma of the renal pelvis and bladder. A case of transitional cell carcinoma associated with phenacetin abuse is presented. The pharmacology of phenacetin metabol...

Bladder carcinoma is the fourth most common cancer in men, however cardiac metastases from the bladder are exceedingly rare. There have been 5 documented cases of transitional cell carcinoma causing cardiac tamponade. There have been 3 documented cases of urothelial carcinoma presenting as cardiac tamponade with positive cytology.1e3 We will discuss a case in which pericardial effusion with tam...

A retrospective survey of young servicemen presenting with transitional cell carcinoma of the bladder aged 40 years or below is presented, 19 such patients having been identified over a 20-year period. The results were compared with those of other similar series. The tumour behaviour appears to vary with age at presentation, its propensity for multifocal presentation, recurrence, progression to...

Ligation of B cell receptors on immature bone marrow B cells, either by an endogenous Ag or by an anti-B cell receptor Ab induces secondary V(D)J gene rearrangements, termed receptor editing. Whether the same signal induces receptor editing in transitional B cells is not clear. In this study, we examined the responses of immature and transitional B cells from V(H)12Vkappa1A Ig transgenic mice t...

Transitional cell cancer (TCC) in the renal pelvis is usually treated by nephro-ureterectomy. In functional or anatomical singular renal units, consecutive chronic hemodialysis will be needed. We present a patient treated by image-guided robotic radiosurgery for definitive tumor control of a T2G3 recurrent transitional cell cancer of the renal pelvis in a singular renal unit after nephro-ureter...

Sir, Paraneoplastic syndromes are defined as nonmetastatic systemic effects that accompany malignant disease. These syndromes may occur in up to 10-15% of malignancies. A few paraneoplastic syndromes have been reported in metastatic transitional cell carcinoma including hypercalcemia, thrombocytosis, eosinophilia, nephrotic syndrome, acanthosis nigricans, dermatomyositis, polymyositis, and leuk...

The length and structure of the transitional zone in the tunica media in the renal artery of adult male cats were investigated. In addition, the volume of the lumen and different layers in transitional and nontransitional zones in the right and left sides were also determined. Morphometrical, histological and stereological studies were performed on 16 renal arteries of 8 adult male cats. After ...

Transitional cell carcinoma of the bladder remains a significant health problem in the United States. Approximately 54,400 new cases of transitional cell carcinoma were reported in the United States in 1999, and an estimated 12,500 deaths were attributed to this cancer.[1] These statistics have remained relatively unchanged over the last several decades despite improvements in both diagnostic i...

We report six patients with upper tract transitional cell neoplasms who were treated by an endourologic approach. Two patients had undergone nephroureterectomy previously, whereas one patient had a single functioning kidney. Two patients were deemed candidates for endourologic procedures secondary to significant comorbid disease precluding major open surgery. The final patient had a low-grade d...