The present work was planned to evaluate the phytoextraction of metal mine tailings, Sarcheshmeh copper mine, SE of Iran, by the endemic plant species Medicago sativa L. (Alfalfa). In this pot experiment, we investigated the effects of seven amendments on the growth of alfalfa and uptaking metals from the mine tailings and stream sediment of tailing dam surface. The mean metal concentrations in...

In order to investigate the accumulation and bio-absorption of lead and cadmium in radish and cress, the present study has been conducted in a completely randomized design in three replicates in a hydroponic growing medium. The first factor includes the plant type at two levels (radish and cress), and the second factor is consisted of lead (Pb) (first experiment) at two levels (50 and 100 mg/L)...

In earlier studies from this laboratory evidence was obtained for a physiological function of tissue factor pathway inhibitor (TFPI) as a regulator of hemostasis capable of preventing thrombotic complications that might otherwise result from exposure of blood to trace amounts of tissue factor (TF). However, it was not possible to conclude that the protective effect of TFPI stemmed solely from i...

This study was undertaken to evaluate the phytoremediation potential of Ficus Benjamina plant for removal polycyclic aromatic hydrocarbons (PAHs): Acenaphthene (ACN), naphthalene (NAP) and phenanthrene (PHE) from contaminated soil. The transplanted into pot containing 4 kg soil spiked with PAHs: ACN, NAP PHE at concentrations 1600, 2000 2400 mg respectively. A separate untreated used as a contr...

This work was designed to assess and compare the heavy metals accumulation phytoremediation ability of some allium species (Garlic; Allium sativum Onion; cepa) grown on two different soils (contaminated Control soils) using standard methods. Heavy (of Cr, Fe, Mn, Ni, Pb, Zn) Concentrations (mg/Kg) were determined atomic absorption spectrophotometry (AAS Model: 210VGP). Plants growth biomass pro...

Environmental pollution with heavy metals is a global disaster that is related tohuman activities. This study was conducted to determine the extent of heavy metalsaccumulation by plant species in Lia industrial city (Qazvin, Iran) and to investigate theremediative capacity of native plant species grown in the contaminated soils. Soil andindustrial wastewater sampling was done radially along tra...

Factor VIIa (VIIa), the serine protease that initiates the coagulation pathways, is catalytically activated upon binding to its cell surface receptor and cofactor tissue factor (TF). This study provides a comprehensive analysis of the functional surface of VIIa by alanine scanning mutagenesis of 112 residues. Residue side chains were defined which contribute to TF binding and factor X hydrolysi...

Tissue factor (TF), formerly known as thromboplastin, is the key initiator of the coagulation cascade; it binds factor VIIa resulting in activation of factor IX and factor X, ultimately leading to fibrin formation. TF expression and activity can be induced in endothelial cells, vascular smooth muscle cells, and monocytes by various stimuli such as cytokines, growth factors, and biogenic amines....

Tissue factor (TF), formerly known as thromboplastin, is the key initiator of the coagulation cascade; it binds factor VIIa resulting in activation of factor IX and factor X, ultimately leading to fibrin formation. TF expression and activity can be induced in endothelial cells, vascular smooth muscle cells, and monocytes by various stimuli such as cytokines, growth factors, and biogenic amines....

Mammary tumors and malignant breast cancer cell lines over-express the coagulation factor, tissue factor (TF). High expression of TF is associated with a poor prognosis in breast cancer. Tissue factor pathway inhibitor (TFPI), the endogenous inhibitor of TF, is constitutively expressed on the endothelium. We hypothesized that TF-expressing tumor cells can bind to immobilized recombinant TFPI, l...