Malaria is a disease activated by type of microscopic parasite transmitted from infected female mosquito bites to humans. fatal that endemic in many regions the world. Quick diagnosis this will be very valuable for patients, as traditional methods require tedious work its detection. Recently, some automated have been proposed exploit hand-crafted feature extraction techniques however, their acc...

Malaria is transmitted when an infected Anopheles mosquito deposits Plasmodium sporozoites in the skin during a bite. Sporozoites are formed within oocysts at the mosquito midgut wall and are released into the hemolymph, from where they invade the salivary glands and are subsequently transmitted to the vertebrate host. We found that a thrombospondin-repeat containing sporozoite-specific protein...

Mosquitoes are common flying insects in the family Culicidae that are found around the world. There are about 3 500 species. The females of most mosquito species suck blood (hematophagy) from other animals, which has made them the deadliest disease vector known, killing millions of people over thousands of years and continuing to kill millions per year by the spread of infectious diseases. Dise...

Background: Blood screening of donors has been routinely conducted to anticipate various infectious diseases transmitted through blood transfusion. However, for malaria not a top priority at the Transfusion Unit (BTU), despite Banda Aceh City being malaria-endemic area. Screening is essential reduce transmission risk and ensure recipient transfusion safety.Objectives: The study aimed determine ...

Rapid diagnostic tests (RDTs) can detect anti-malaria antibodies in human blood. As they can detect parasite infection at the low parasite density, they are useful in endemic areas where light infection and/or re-infection of parasites are common. Thus, malaria antibody tests can be used for screening bloods in blood banks to prevent transfusion-transmitted malaria (TTM), an emerging problem in...

Brazil, a country of continental proportions, presents three profiles of malaria transmission. The first and most important numerically, occurs inside the Amazon. The Amazon accounts for approximately 60% of the nation's territory and approximately 13% of the Brazilian population. This region hosts 99.5% of the nation's malaria cases, which are predominantly caused by Plasmodium vivax (i.e., 82...

Mefloquine hydrochloride [WR 142,490; alpha-(2-piperidyl)-2,8-bis(trifluoromethyl)-4-quinolinemethanol hydrochloride] was tested for suppressive effect on sporozoite-induced malaria in nonimmune volunteers living in an area where malaria is not naturally transmitted. Single doses of 250 mg were given at weekly intervals, 500 mg at intervals of 2 weeks and 1,000 mg at intervals of 4 weeks, to me...

Every year up to about 300 million people are infected by malaria, an infectious disease caused by Plasmodium species parasites. Consequently, nearly 660, 000 deaths occur. Infected female Anophele mosquitoes transmit the parasite to humans through their salivary glands. Although there are other species that cause malaria, P. falciparum is the most dangerous type that infects and is transmitted...

A mosquito needs to bite at least twice for malaria transmission to occur: once to acquire parasites and, after these parasites complete their development in their mosquito host, once to transmit the parasites to the next vertebrate host. Here we investigate the relationship between temperature, parasite development, and biting frequency in a mosquito-rodent malaria model system. We show that t...

Transmission of insect-borne diseases is shaped by the interactions among parasites, vectors, and hosts. Any factor that alters movement of infected vectors from infected to uninfeced hosts will in turn alter pathogen spread. In this paper, we study one such pathogen-vector-host system, avian malaria in pigeons transmitted by fly ectoparasites, where both two-way and three-way interactions play...