introduction: acute rejection of renal transplant is a serious and common systemic inflammatory disorder which leads to decreasing half-life of transplant organ. current diagnoses method is an invasive biopsy procedure on allogtraft kidney. therefore, applying a novel and noninvasive diagnostic method such as granzym b level in acute renal transplantation could help patients and improves surviv...

Chronic antibody-mediated rejection (ABMR) is a major cause of the transplant renal interstitial fibrosis and transplanted kidney epithelial cell transdifferentiation is one of the main mechanisms. The transforming growth factor (TGF)-β1/integrin-linked kinase (ILK) signaling pathway has a significant role in the epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells; however...

BACKGROUND Renal transplant recipients have increased risk for developing malignant diseases because of immunosuppression or donor-to-recipient transmission. Malignant rhabdoid tumor (MRT) is a rare, highly aggressive and lethal tumor primarily affecting the kidney of infants and young children. MRT has not been reported in the renal allograft of an adult recipient after kidney transplantation....

Objective: To evaluate the effect of dialysis and kidney transplantation on serum levels of several tumor markers such as PSA, AFP, CA125, CA19- 9, CA15-3, CEA and to compare with normal age matched controls. Methods: Between September of 2000 and July of 2001, the following tumor markers: PSA, AFP, CA125, CA19-9, CA15-3 and CEA were measured by ELISA Method in 29 hemodialyzed patients (group A...

BACKGROUND Histopathological assessment of kidney prior to transplantation is a part of the comprehensive information gathered on the transplanted organ. In our study we monitor the influence of individual morphological findings (glomeruli, arteries, arterioles, interstitium, tubules) and degree of histopathological changes in the kidney function after transplantation. METHODS From 1994 to 19...

BACKGROUND Polycystic Kidney Disease (PKD) is a genetic condition in which dedifferentiated and highly proliferative epithelial cells form renal cysts and is frequently treated by renal transplantation. Studies have reported that bone marrow-derived cells give rise to renal epithelial cells, particularly following renal injury as often occurs during transplantation. This raises the possibility ...

Today successful kidney transplantation procedures, techniques and immunosuppression protocols are a consequence of extensive research on animal models. During every transplantation surgery there are two crucial points for the success of the entire procedure: vascular (arterial end venous) and ureteral or ureterovesical anastomosis. Renal artery and vein of the donor kidney can be anastomosed e...

objective: to evaluate the effect of dialysis and kidney transplantation on serum levels of several tumor markers such as psa, afp, ca125, ca19- 9, ca15-3, cea and to compare with normal age matched controls. methods: between september of 2000 and july of 2001, the following tumor markers: psa, afp, ca125, ca19-9, ca15-3 and cea were measured by elisa method in 29 hemodialyzed patients (group a...

Arterioenteric fistula (AEF) on a kidney graft site is a rare cause of massive lower gastrointestinal bleeding (LGIB). Emergency angiography with concomitant endovascular repair is an efficient and safe approach in controlling the acute bleeding and stabilizing patients with life-threatening bleeding from AEF. We report a 42-year-old male who underwent allograft renal transplantation in the rig...