background: infertility is common among couples of child-bearing age and ap-proximately half of known causes of primary infertility are attributable to male factor. it is still unclear whether the injurious effects of cigarette smoking on sperm characteristics and infertility are due to nicotine. therefore, the present study investigated the effects of orally administered of nicotine on sperm c...

Objective Opioid consumption has been widely increasing across the globe; however, it can cause adverse effects on the body. Morphine, an opioid, can reduce sex hormones and fertility. Withania somnifera (WS) is a traditional herb used to improve sexual activities. This study strives to investigate the effect of WS on sex hormones and gonadotropins in addicted male rats. MaterialsAndMethods In ...

there are many discrepancies around the effect of sex hormones on spatial learning and memory in rodents. the aim of the present study was to investigate the effects of chronic administration of estradiol (es) and testosterone (tes) on spatial memory in adult castrated male rats. cholinesterase activity of the hippocampus in treated animals was also measured to seek if hormonal treatment can ch...

Background: Corrosive esophageal burns have high morbidity and mortality. The effective treatment is controversial. In our study, we aimed to examine the effects of resveratrol (RSV) platelet rich plasma (PRP) on healing in corrosive esophagitis model rats. 
 Material methods: A total 24 rats were randomly divided into 4 groups each as esophagitis, control, PRP RSV groups. No was administe...

Angiotensin receptor blockers are well known for their therapeutic efficacy and fimasartan has been used safely efficiently since 2010 in the treatment of hypertension. The study aimed to examine anti-inflammatory effect egg albumin-induced inflammation rats. Rats were treated with diclofenac (25 mg/kg, intraperitoneally) or at two different doses (3 10 intraperitoneally). increase thickness pa...

Objects: The phytochemical screening and the antihyperglycemic impact of Pelargonium gravelens were performed to judge ethanol extract using alloxan-induced diabetic rats. Methods: Intragastric ethanolic amount level 220 mg/kg body weight given alloxan-encouraged male albino rats for four weeks. Diabetic control assumed equivalent quantity vehicle (Dimethylsulfoxide, DMSO) processed together wi...

Background: The effect of the wild SKEO on activities and genes expression of hepatic glucokinase (GK), glycogen phosphorylase (GP) and phosphoenolpyruvate carboxykinase (PEPCK) in normal and diabetic rats was evaluated. Materials and Methods: The wild SKEO was orally administered at dose (100 mg/kg per day) to normal, as well as diabetic rats for 21 days. The levels of mRNA were determined usi...

background: poly cystic ovary syndrome is one of the most common female endocrine disorders. one of the side effects of pcos is oxidative stress.. here we investigated antioxidants effects of thymus vulgaris ethanoli extract on experimental pcos induced rats by estradiol-valerat (ppa). methods : wistar female rat (n=70) were divided into 7 groups including c1: an equal volume of (0.9% nacl) as ...

intracerebroventricular (icv) injection of streptozotocin (stz) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic alzheimer’s disease (sad). epidemiological studies suggest that non-steroidal anti-inflammatory drugs (nsaids) could delay or slow the clinical expression of sad. therefore, the beneficial e...

introduction: this study aimed to examine the effects of induced inflammatory tooth pain on anxiety level in adult male rats. methods: the mandibular incisors of 56 adult male rats were cut off and prefabricated crowns were fixed on the teeth. formalin and capsaicin were injected intradentally to induce inflammatory tooth pain. diazepam treated group received diazepam 30 minutes before intraden...