BACKGROUND To investigate the reasons and risk factors for modification of the first combined antiretroviral therapy (cART) currently used for HIV infected patients who were treatment naïve in Shanghai China. METHODS Making a retrospective observational research on treatment naïve patients with HIV infection who initiated cART during the period of September 1st 2005---December 1st 2013. The d...

OBJECTIVE To assess the safety and efficacy of a low-dose magnesium sulfate regimen for the management of eclampsia in Indian women. METHODS A loading dose consisting of 3g of magnesium sulfate intravenously plus 5g intramuscularly (2.5g in each buttock) was followed by 2.5g intramuscularly every 4hours, for 24hours beyond the last seizure. In a first phase, which spanned 2001 and 2002, the r...

OBJECTIVE Better weight loss outcomes are achieved in adults and youth who adhere to obesity treatment regimens (i.e., session attendance and prescribed changes in weight control behaviors). However, more research is needed regarding children's adherence to a range of behaviors relevant for weight maintenance over long-term follow-up. DESIGN AND METHODS Overweight children (N = 101, aged 7-12...

BACKGROUND Paclitaxel and carboplatin given every 3 weeks is standard treatment for advanced ovarian carcinoma. Attempts to improve patient survival by including other drugs have yielded disappointing results. We compared a conventional regimen of paclitaxel and carboplatin with a dose-dense weekly regimen in women with advanced ovarian cancer. METHODS Patients with stage II to IV epithelial ...

Background: The role and proper dose of pralidoxime in the treatment of Organophosphorus (OP) compounds poisoning is an unresolved issue .This study was designed to compare the regimen recommended by the World Health Organization (WHO) with the commonly used standard regimen of pralidoxime. Methods: This was a randomized open labeled prospective study on OP poisoned patients admitted to JSS Hos...

OBJECTIVES To compare a new low-dose warfarin induction regimen with the Fennerty regimen in elderly inpatients. DESIGN Age-stratified, randomized prospective study. SUBJECTS 120 age-stratified elderly inpatients. INTERVENTIONS Each patient was randomized to either the new induction regimen or to a modified Fennerty regimen. MAIN OUTCOMES MEASURES Days to therapeutic International Norma...

Objective: This study examines the effect of the addition of IMOD, a novel multi-herbal drug to the highly active anti-retroviral therapy (HAART) regimen, on the immunological status of HIV-positive patients. Materials and Methods: A randomized two-parallel-group (HAART group versus HAART+IMOD group), pretest-posttest design was used.Sixty patients with indications for treatment with the HAART ...

basal cell carcinoma (bcc) is the most common cancer among humans, and the standard treatment is surgery. other modalities are reserved as a second line of treatment. topical chemotherapy may be used in primary bcc. systemic chemotherapy has no role in the primary treatment of bcc, although it may be efficacious in metastatic cases. we report the case of a patient with persistent recurrent bcc ...

background helicobacter pylori (h. pylori) is one of the most common bacterial infections worldwide. we designed a study to compare the efficacy of 14-day hybrid regimen with 10-day concomitant therapy for h. pylori eradication in iran. methods 252 patients with naïve h. pylori infection were randomly divided to receive either hybrid regimen (pantoprazole 40 mg, and amoxicillin 1 gr twice daily...

BACKGROUND All-oral regimens are associated with higher effectiveness and shorter treatment duration for chronic hepatitis C. Given its superior effect and enormous patients in China, clinicians or patients may be compelled to consider delaying treatment for all-oral regimen. OBJECTIVE To estimate cost-effectiveness of delaying treatment for all-oral regimen in the subsequent years under diff...