PURPOSE Facial esthetics play an important role in social interactions. However, children with a repaired complete unilateral cleft lip and palate usually show some disfigurement of the nasolabial area. To date, few studies have assessed the nasolabial appearance after different treatment protocols. The aim of the present study was to compare the nasolabial esthetics after 1- and 3-stage treatm...

Due to the impact of climate change, the process of salinity intrusion occurs frequently in coastal areas of Vietnam. The main objective of this study is therefore to try diff erent nanofi ltration (NF) processes (such as single-stage and dual-stage NF) to treat brackish water for residential areas in Thu Bon river basin, where the salinity varies signifi cant with seas...

Not only is the incidence of lung cancer increasing around the world, this disease has become the leading cause of cancer death. Since lung cancer kills 85% to 90% of its victims, it is recognized as one of the most difficult to cure diseases. Although the therapeutic results are quite unsatisfactory as a whole, earlier stages of lung cancer, stages IA and IB show better therapeutic results (Ta...

BACKGROUND There is no clear consensus regarding systemic treatment of early-stage ovarian cancer (OC). Clinical trials are challenging because of the relatively low incidence and good prognosis. Initial results of the International Collaborative Ovarian Neoplasm (ICON)1 trial demonstrated benefit in both overall survival (OS) and recurrence-free survival (RFS) with adjuvant chemotherapy. We re...

HYPOTHESIS The clinical treatment of patients with stage IV melanoma according to criteria of the American Joint Committee on Cancer (AJCC) is controversial because the 5-year survival rate is approximately 5%. Specific clinicopathologic factors are predictive of survival following curative surgery. DESIGN Cohort analysis of 1574 successive patients undergoing surgical resection of metastatic...

Although T2,N0,M0 esophageal adenocarcinoma is grouped with other locoregional disease by NCCN, no consensus exists about how it should be treated. One of the inherent complexities of treating T2,N0,M0 esophageal adenocarcinoma is the inaccuracy of the clinical staging. In addition, conflicting evidence exists about whether neoadjuvant therapy adds any benefit to esophagectomy. A 52-year-old pa...

Patients should be referred for cardiac transplantation only after all other means of management of congestive heart failure have been attempted and have been unsuccessful (table 3). An adequate therapeutic trial of conventional and experimental agents including beta blockade and vesnarinone should be completed and be shown to be unsuccessful before transplantation is considered in patients in ...