Menopausal symptoms experienced by women vary widely, and while many women transition through menopause with manageable symptoms, others experience severe symptoms, which may impair their quality of life. The purpose of this study was to determine the effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms. A randomised, triple-blind, controlled trial design was us...

Two new steroidal saponins and two known flavonoid glycosides were isolated from the fruits of Tribulus terrestris. Their structures were assigned by spectroscopic analysis and chemical reaction as 26-O-beta-D-glucopyranosyl-(25R)-5 alpha-furostan-12-one-3beta,22 alpha,26-triol-3-O-beta-D-glucopyranosyl (1 --> 2)-beta-D-glucopyranosyl(1 --> 4)-beta-D-galactopyranoside (1), 26-O-beta-D-glucopyra...

Twelve new steroidal saponins, including eleven furostanol saponins, terrestrinin J-T (1-11), and one spirostanol saponin, terrestrinin U (12), together with seven known steroidal saponins 13-19 were isolated from T. terrestris. The structures of the new compounds were established on the basis of spectroscopic data, including 1D and 2D NMR and HRESIMS, and comparisons with published data.

PURPOSE Tribulus terrestris has been used as an aphrodisiac. However, little is known about the effects and mechanism of action of T. terrestris on penile erection. Therefore, the effect of a T. terrestris extract and the mechanism of action of the extract on relaxation of the corpus cavernosum (CC) were investigated. The erectogenic effects of an oral preparation of the extract were also asses...

This is a qualitative-quantitative study based on hospital records of female patients of reproductive age, presenting sexual dysfunction, and treated with 250 mg Tribulus terrestris extract (1 tablet thrice daily for 90 days). Safety monitoring included vital signs, physical examination, laboratory tests, and occurrence of adverse events. Efficacy analysis included results of the Female Sexual ...

Amrithadi Churnam - a compound ayurvedic preparation made up of Tinospora cordifolia, Salacia prenoides, Curcuma longa, Tribulus terrestris and Emblica Officinalis was screened for its antidiabetic activity. From the studies it could be established that Amrithadi churnam at a dose level of 100mg/kg b.w. was the optimum dose in alloxan diabetic rats. No toxic effects were observed as evidenced b...

Tribulus terrestris L. (Family: Zygophyllaceae) has been used extensively for various human ailments by different traditional systems of medicine including Ayurveda. Recently, the anti-proliferative effect of this plant against breast cancer cells was reported. In the present study, the cytotoxic and antitumour effects of the methanolic extract of T. terrestris fruits were analysed. On in vitro...

The aim of this study was to assess the sperm quality and testicular histomorphometry of Wistar rats supplemented with extract and fractions of fruits of Tribulus terrestris L. The ethanolic extract was obtained by dynamic maceration of spray-dried fruit. This extract was fractionated by liquid-liquid partition, using increasing polarity solvents. Twenty male rats were separated in four groups,...

We evaluate the analgesic and anti-inflammatory potential of ethanol extract of Tribulus terrestris L. (TT) leaves on Wistar rats. Analgesic and anti-inflammatory potential of the ethanol extract of the TT leaves at doses of 50, 100 & 200 mg/kg was evaluated against the standard drug indomethacin at a dose of 20 mg/kg, p.o. Adult Wistar rats of either sex of six numbers in each group was undert...