introduction: cisplatin is an anti-cancer drug used in chemotherapy. one of the limiting side effects of cisplatin is decreasing genital gland function, azoospermia and oligospermia. tribulus terrestris (tt) has been used as an aphrodisiac. the present study amid to investigate the protective effect of tt hydroalcoholic extract against cisplatin-induced apoptisis on testis in mice. methods: mal...

Solid Lipid Nanoparticles (SLN) have been prepared by high-pressure homogenization and optimized in order to protect ferulic acid from Ferula assa-foetida L. extract. The influence of lipid surfactant concentration on the mean particle size (Z-Ave), polydispersity index (PDI), zeta potential (ZP) SLN was analyzed. In addition, other parameters for preparation acid-loaded nanoparticles, such as ...

ferula assa-foetida l . is distributed throughout central asia and mediterranean area and grows wildly in iran and afghanistan. asafoetida is an oleo-gum-resin that is the exudates of the roots of ferula assa-foetida and some other ferula species. in iranian traditional medicine, asafoetida is considered to be sedative, analgesic, carminative, antispasmodic, diuretic, antihelmintic, emmenagogue...

Tribulus terrestris is used as a urinary anti-infective in folk medicine. To validate this use, the in vitro antibacterial activity of methanolic extracts of different parts (fruits, stems plus leaves and roots) of T. terrestris L. growing in Iran was evaluated against four reference bacteria by broth dilution assay and agar diffusion assay. The MIC value of the methanolic extracts of fruits an...

Geeldikkop was induced in a sheep by dosing it orally with a crude extract of the steroidal saponins from Tribulus terrestris. GC-MS analysis of the sheep's ruminal contents, bile, faeces and urine for free and conjugated sapogenins, revealed the general features of the metabolic pathway by which diosgenin and yamogenin glycosides were converted into the glucuronides of epismilagenin and episar...

OBJECTIVE Antioxidant, anti-inflammatory, analgesic and antimicrobial activities of Tribulus terrestris (T. terrestris) could be helpful in the treatment of acute pancreatitis; thus, this study was designed to investigate the effects of T. terrestris on cerulein-induced acute pancreatitis in mice. MATERIALS AND METHODS Three doses (100, 200 and 400 mg/kg) of T. terrestris hydro-alcoholic extr...

This study was conducted to determine the effect of Tribulus terrestis extract on urinary risk factors in normal and 18 normal subjects were selected and administered once daily with 10 mL of T. terrestris extract for one week. Serum, urine collected between 10 pm and 6 am, and 24 h urine samples were analysed for urinary risk factors for stone formation on day 0 and day 8 after administration ...