'The discovery of the growing spread of trichomoniasis is due to improved methods of research. Increased morbidity has accompanied inadequate treatment and is especially due to the confused view of the problem, which is a joint task for gynaecologists, venereologists, and urologists. It may be described as a venereal disease because it is transmitted in the great majority of cases by sexual int...

This paper describes the TDO model of media, which describes media as they are viewing by multimedia authors and the authoring software they use. This model is the basis of the MSPEC medium specification language, which is used to configure a style sheet system for multimedia authoring systems. The TDO model is compared to two other models drawn from multimedia and intelligent systems research ...

The enzyme TDO (tryptophan 2,3-dioxygenase; TDO-2 in Caenorhabditis elegans) is a potential therapeutic target to cancer but is also thought to regulate proteotoxic events seen in the progression of neurodegenerative diseases. To better understand its function and develop specific compounds that target TDO we need to understand the structure of this molecule. In C. elegans we compared multiple ...

We present a novel test architecture which combines IEEE 1149.1 Boundary-Scan with a Memory Built-In Self-Test. The TDI pin is used for serially shifting in the test data into a test data register which is connected to the memory. The finite state machine of the TAP controller performs the memory test algorithm. The test response is shifted out via the TDO pin for off-chip analyses. The test ar...

From a protein structural viewpoint, tryptophan is often considered an inert structural amino acid, playing a role as a hydrophobic anchor in membrane proteins or as part of the hydrophobic core of soluble proteins. However, tryptophan is the only polyaromatic amino acid and, from a chemical viewpoint, possesses unique reactivity owing to the electron-richness of the indole system. This reactiv...

Objectives: Congenital diarrhea and enteropathies linked to epithelial structural abnormalities constitute 3 different rare diseases: the tufting (TE; EPCAM SPINT2 mutations), microvillous inclusion disease (MVID; MYO5B STX3 tricho-hepato-enteric syndrome (THE; TTC37 SKIV2L mutations). Moreover, enteroendocrine deficiencies (ED; PCSK1 NEUROG3 mutations) share common clinical characteristics wit...