background: in spite of sufficient knowledge about phenotypic variation of trichomonas vaginalis , its genetic characteristics are poorly understood. we carried out a molecular epidemiology study in which in vitro metronidazole susceptibility of t. vaginalis isolates was considered. methods : this study was conducted on 862 women admitted to gynecology clinics in hamadan, west of iran, during 2...

Trichomonas vaginalis is a flagellated lumen-dwelling extracellular protozoan parasite that causes human trichomoniasis via sexual intercourse. Human neutrophils play a crucial role in acute tissue inflammatory responses in T. vaginalis infection. In this study, we investigated the signaling mechanism of neutrophil responses when stimulated with T. vaginalis-derived secretory products (TvSP), w...

Despite the declining rate of sexually transmitted diseases in developed countries, trichomoniasis is still one of the most common venereal infections. While diagnosis of this condition is commonly based on the microscopic wet-mount method, culture remains the most accurate single procedure for detecting the presence of Trichomonas vaginalis in clinical samples. In the present study, the effica...

Trichomoniasis is a common sexually transmitted disease with an estimated incidence of 4 million to 8 million cases a year in the United States. The most commonly used method of diagnosis is a direct microscopic observation (wet mount) of vaginal secretions and, although both rapid and inexpensive, the sensitivity of this technique is generally 50 to 70%. We developed an indirect enzyme-linked ...

BACKGROUND The aims of this study were to examine the prevalence of trichomoniasis among women aged 18 to 48 yr in Ardabil, northwestern Iran and the relationship between demographic factors and the risk of infection. METHODS Vaginal discharge samples of 914 women aged 18 to 48 yr, referred to Gynecology Clinic of Sabalan Hospital of Ardabil, Iran in 2014, were collected and Trichomonas vagin...

  To determine the prevalence of trichomoniasis in Sirjan city, the vaginal discharges of 500 women were examined by direct smear and culture methods from June to December 1992. ( Two hundred thirty women referred to vali-asr polyclinic and 270 to the health center number 3). The mean age of the women was 30 years and a higher percentage of referrals were between 30-34 years. In respect to the...

The in vitro activities of tinidazole and metronidazole against Trichomonas vaginalis isolates clinically resistant to metronidazole were compared. Minimal lethal concentrations (MLCs) of tinidazole were significantly lower than MLCs of metronidazole. Increased metronidazole resistance correlated with increased tinidazole resistance. These data support a role for tinidazole in the treatment of ...

Survey of urinary schistosomiasis and trichomoniasis was conducted among 830 inhabitants of Ikao village, in Owan local government area of Edo State, Nigeria Between October, 1999 and February, 2000. Of these, 178 (21.4%) excreted Schistosoma haematobium ova in their urine. School children were more infected than the farmers and petty traders. Males were more infected than the female counterpar...

It has been suggested that high zinc concentrations found in men may prevent Trichomonas vaginalis from being established in the male reproductive tract. In this investigation T vaginalis was readily killed at concentrations of zinc that occur in the prostatic fluid of healthy men (minimum trichomonacidal concentration (MTC) of 6.4 mmol/l). T vaginalis was also shown to be killed by human prost...