BACKGROUND Chronic soil-transmitted helminth (STH) infections are associated with effects on systemic immune responses that could be caused by alterations in immune homeostasis. To investigate this, we measured the impact in children of STH infections on cytokine responses and gene expression in unstimulated blood. METHODOLOGY/PRINCIPAL FINDINGS Sixty children were classified as having chroni...

This article involves the fauna and ecological features of helminths cattle in various biocenoses Uzbekistan. Based on many years our own research analysis literature data, 71 species were identified Uzbekistan, which 12 belong to class cestodes, trematodes 47 nematodes. Of Republic, 1 (Stephanofilaria assamensis) was noted by us for first time CIS 11 (Moniezia alba, Trichocephalus globulosa, B...

BACKGROUND: Few studies have assessed the burden of tropical diseases among migrants into non-endemic countries. AIM: This study aimed to systematically review existing data prevalence globally, including neglected globally. MATERIALS AND METHODS: The authors conducted a systematic reporting (including seroprevalence) following PRISMA guidelines and based on database from PUBMED, WoS, PROQUEST....

Two commercially available diagnostic tools (Tro-Bio ELISA and ICT card test) were used to detect circulating filarial antigen of Wuchereria bancrofti infections among Indian expatriate workers in Saudi Arabia. Daytime serum samples collected from 302 individuals (210 men and 92 women) were tested. Night blood surveys for microfilaraemia were restricted to those individuals who became positive ...

The whipworm of humans, Trichuris trichiura, is responsible for a neglected tropical disease (NTD) of major importance in tropical and subtropical countries of the world. Whipworms also infect animal hosts, including pigs, dogs and non-human primates, cause clinical disease (trichuriasis) similar to that of humans. Although Trichuris species are usually considered to be host specific, it is not...

The relationship between Toxocara infection and epilepsy was previously demonstrated by several case-control studies and case reports. These previous studies were often based on the enzyme-linked immunosorbent assay (ELISA) using Toxocara excretory-secretory antigens, which are not specific due to cross-reactivity with other parasitic infections such as ascariasis, trichuriasis, and anisakiasis...

Helminth infections are responsible for a considerable public health burden, yet the current drug armamentarium is small. Given the high cost of drug discovery and development, the high failure rates and the long duration to develop novel treatments, drug repurposing circumvents these obstacles by finding new uses for compounds other than those they were initially intended to treat. In the pres...