SETTING Existing tuberculosis control strategies in Vietnam are based on symptomatic patients attending health services for investigation. This approach has not resulted in substantial reductions in the prevalence of tuberculosis disease, despite the National Tuberculosis Program achieving high treatment completion rates. Alternative approaches are being considered. OBJECTIVE To determine the...

OBJECTIVE The rapid differentiation between Mycobacterium tuberculosis and nontuberculous mycobacteria is fundamental for patients co-infected with tuberculosis and HIV. To that end, we use two methods in our laboratory: detection of cord factor and PCR-restriction enzyme analysis (PRA). The objective of this study was to evaluate the accuracy of a screening test on solid medium as a rapid meth...

The elimination of tuberculosis in Europe is a key public health priority, yet unprecedented levels of migration, especially from low-income or middle-income countries, pose challenges to achieving this goal. The overall incidence of tuberculosis in migrants is increasing in several countries, and—for example—migrants comprise more than 70% of all newly diagnosed cases in the UK, Sweden, the Ne...

Background: Tuberculosis remains a major public health problem in Nigeria and the world at large. Substantial number of cases of tuberculosis occurs in children, especially in this era of HIV pandemic. Chest radiograph is an important examination in evaluation for pulmonary tuberculosis. There is paucity of literature on the chest radiographic features predictive of HIV in pulmonary tuberculosi...

BACKGROUND In Pakistan, like many Asian countries, a large proportion of healthcare is provided through the private sector. We evaluated a systematic screening strategy to identify people with tuberculosis in private facilities in Karachi and assessed the approaches' ability to diagnose patients earlier in their disease progression. METHODS AND FINDINGS Lay workers at 89 private clinics and a...

This paper presents a highly sensitive optical biosensor and novel sample collection strategy to allow for rapid onsite screening of tuberculosis patients. The technique presented herein was field tested and envisaged to be potentially useful in third world countries with high incidences of tuberculosis or at disparate locations void of proper tuberculosis diagnostic laboratories. The rapid scr...

PULMONARY tuberculosis is a classic disease that satisfies all the criteria for screening (Wilson and Junger, 1968) and has been carried out extensively with mass radiography. However its contribution to lowering the risk of infection by tuberculosis is contradictory (Colley, 1974). Pulmonary tuberculosis screening by mass miniature radiography has been standard practice in the Malaysian Armed ...

INTRODUCTION There has been an increase in the incidence of tuberculosis infection in recent years, due to the increasing use of drugs inhibiting tumour necrosis factor-alpha (anti-TNFα) in the treatment of inflammatory diseases. CASE REPORT We report the case of a male patient being treated with infliximab (anti-TNFα) who developed disseminated tuberculosis with ocular involvement. CONCLUS...

Although recent studies have reported otherwise, previous conventional wisdom has held that one-half to twothirds of pregnant women with tuberculosis are asymptomatic. If true, this has important implications for screening programs. Charts of all patients with cultureproven Mycobacterium tuberculosis in Rhode Island between 1987 and 1991 were reviewed. One-third of women aged 21 to 32 years wit...

A screening test for the diagnosis of tuberculosis by immunodot (IDt) is described, using an antigen of Mycobacterium tuberculosis, namely, a 38-kDa glycoprotein which has shown great specificity in previous serologic analyses. The test was used to examine 28 sera from patients with lung tuberculosis. Of these, 85% were positive by micro-ELISA and by the IDt test herein described. Control sera ...