BACKGROUND Multidrug-resistant (MDR) tuberculosis can be acquired through de-novo mutation during tuberculosis treatment or through transmission from other individuals with active MDR tuberculosis. Understanding the balance between these two mechanisms is essential when allocating resources for MDR tuberculosis. We aimed to create a dynamic transmission model of an MDR tuberculosis epidemic to ...

Lupus vulgaris is a progressive form of skin tuberculosis occurring in the patients with a moderate to high degree of immunity. It is reported to be the commonest type of skin tuberculosis. Our case was a 40 year-old man who referred with multiple, erythematous, annular plaques, 30-50 mm in diameter with active margin and few studded pustules throughout the lesions. Our first impression was tin...

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which usually affects the lungs and can lead to death. Treating infection provides a cure for TB, but involves use of multiple drugs. In this context, pharmacist health professional with skills abilities monitor patients optimize their treatment. Given this, present review aimed gather articles that address pharmac...

Tuberculosis is still a major burden of disease in Indonesia. The highly transmissible, and if it resistant to drugs, treatment can be take long time. Patients with pulmonary tuberculosis will difficult cure there no regular treatment. This study aims identify factors related patient adherence Sorong City. uses cross-sectional design 72 respondents. Data collection through interviews structured...

With an unstable epidemic situation for tuberculosis, with the development of a pandemic another etiology, importance effective treatment disease increases. The results observation 326 patients were used and influence individual predictors efficacy, including gene polymorphisms xenobiotic biotransformation enzymes patient adherence to analyzed. value patient’s commitment as predictor effectiven...

Tuberculosis is a global burden with most cases occurring in developing countries. After the implementation of Directly Observed Treatment Short-course (DOTS), incidence tuberculosis decreased. Despite, studies reported constraints implementing this program. This study aims to describe challenges DOTS countries narratively. Methods: search strategy through PUBMED was used identify relevant arti...

tuberculosis pericarditis as a potentially fatal complication of tuberculosis requires effective diagnosis and treatment. we evaluated the efficacy of interferon-gamma (ifn-gamma) and adenosine deaminase (ada) for diagnosing tuberculosis pericarditis in a cohort of iranian patients presenting with pericarditis. we enrolled 38 patients with presentation of pericarditis. all patients underwent di...

Background & Aims: Tuberculosis is one of the most important causes of mortality in the world and if it is not treated, 50 – 65% of patients would die in five years. Chest X-ray has an important role in the diagnosis of TB and early diagnosis and treatment prevent tuberculosis transmission. In this study we evaluated radiologic manifestations of patients with smear positive pulmonary tubercu...

Efficient tuberculosis treatment requires the use of good quality medicines. The present study developed a method of dosage by High Performance Liquid Chromatography (HPLC) coupled with the dissolution of a combination of fixed doses of four anti-tuberculous (Isoniazid, Pyrazinamide, Ethambutol Hydrochlorate, Rifampicine). The elaborated protocol was thereafter used to assess the quality of med...