Mechanisms of articular cartilage growth and maturation have been elucidated by studying composition-function dynamics during in vivo development and in vitro culture with stimuli such as insulin-like growth factor-1 (IGF-1) and transforming growth factor-beta 1 (TGF-beta1). This study tested the hypothesis that IGF-1 and TGF-beta1 regulate immature cartilage compressive moduli and Poisson's ra...

Ž The performance of four commonly used density functionals VWN, BLYP, BP91, and Becke’s original three-parameter approximation to the adiabatic connection formula, referred to herein as the adiabatic connection method or . w ACM was studied with a series of six Gaussian-type atomic basis sets DZP, Ž .x 6]31G**, DZVP, TZVP, TZ2P, and uncontracted aug-cc-pVTZ UCC . The geometries and dipole mome...

Purpose:Urothelial cell carcinoma (UCC) rapidly progresses from superficial tomuscle-invasive tumors. The key molecules involved in metastatic progression and its early detection require clarification. The present study defines a seminal role of themetastasis-associated geneMDA-9/Syntenin inUCCprogression. ExperimentalDesign: Expression pattern ofMDA-9/Synteninwas examined in 44 primaryUCC and ...

Der Beitrag enthält eine Zusammenfassung der Dissertation ”Approximability of Cycle Covers and Smoothed Analysis of Binary Search Trees“. Eine Zyklenüberdeckung eines Graphen ist ein Teilgraph, der nur aus Zyklen besteht, so dass jeder Knoten Teil genau eines Zyklus ist. Bei einer L-Zyklenüberdeckung muss zusätzlich die Länge jedes Zyklus in der Menge L liegen. Im ersten Teil der Dissertation w...

BACKGROUND Aristolochic acid I (AAI) has been implicated in urothelial cell carcinoma (UCC) in humans. However, whether AAI promotes invasion/migration of UCC has not been established. METHODS A study of human UCC TSGH cells cultured with AAI was conducted. Cell viability, the effects of AAI on the activity of matrix metalloproteinase (MMP)-9, the abilities of invasion/migration and the migra...

Two nearly identical unicyanobacterial consortia (UCC) were previously isolated from benthic microbial mats that occur in a heliothermal saline lake in northern Washington State. Carbohydrates are a primary source of carbon and energy for most heterotrophic bacteria. Since CO2 is the only carbon source provided, the cyanobacterium must provide a source of carbon to the heterotrophs. Available g...

The Chinese Loess Plateau (CLP) is the largest loess deposit on Earth with expansive surface-exposed source rocks of varying origins, ages, and history. Here, we present abundances elements representative palaeosol samples from seven classic sections CLP. Most elements, including soluble (e.g. Rb Cs), show significant correlations La or Al2O3. These indicate that these are hosted absorbed in pa...

CONTEXT The European Association of Urology (EAU) Guideline Group for urothelial cell carcinoma of the upper urinary tract (UUT-UCC) has prepared new guidelines to aid clinicians in assessing the current evidence-based management of UUT-UCC and to incorporate present recommendations into daily clinical practice. OBJECTIVE This paper provides a brief overview of the EAU guidelines on UUT-UCC a...

PURPOSE To analyze the role and translational potential for hypermethylation of CpG islands and shores in the regulation of small RNAs within urothelial cell carcinoma (UCC). To examine microRNAs (miR) and mirtrons, a new class of RNA located within gene introns and processed in a Drosha-independent manner. EXPERIMENTAL DESIGN The methylation status of 865 small RNAs was evaluated in normal a...

OBJECTIVE Urgent care centres' (UCCs) hours were developed with the aim of reducing inappropriate emergency department (ED) attendances in England. We aimed to examine the presenting complaint and outcomes of care in 2 general practitioner (GP)-led UCCs with extended opening times. DESIGN Retrospective observational epidemiological study using routinely collected data. SETTING 2 GP-led UCCs...