The sun protection factor (SPF) has widely been used to evaluate the protective value of sunscreens. However, SPF only reflects the effectiveness of the sunscreen to protect against acute sunburn which is mainly due to ultraviolet B (UVB) radiation. The deleterious effects of UVB are well known and UVB was believed in the past to be the spectrum responsible for the damages arising from ultravio...

Exposure to ultraviolet radiation (UVR) and airborne pollution, particularly in the form of particulate matter sized 2.5 μm (PM2.5), is associated with signs skin aging inflammation. Damage from UVR PM2.5 believed be result oxidative stress, therefore, we examined effects a novel composition containing three antioxidants an vitro model system order better understand their potential. We focused ...

We present here that Heat shock protein 90 (Hsp90) inhibitor 17-(allylamino)-17demethoxygeldanamycin (17AAG), when topically applied to mouse skin, inhibits ultraviolet radiation (UVR)-induced development of cutaneous squamous cell carcinoma (SCC). In these experiments, DMSO:acetone (1:40 v/v) solution of 17AAG (500nmol) was applied topically to mouse skin in conjunction with each UVR exposure ...

Ultraviolet radiation (UVR) of the skin results in immune suppression to antigens encountered shortly after the exposure. The pathways leading to the downregulation in immunity are complex, initiated by chromophores located at the surface of the skin and ending with the generation of immunosuppressive mediators and regulatory cells. Ultraviolet-induced immunosuppression can be considered not on...

The exposure of organisms to ultraviolet radiation (UVR) is characterized by the climatology (annual cycle) and the variance (anomalies) of biologically-weighted irradiances at eight geographical locations in austral South America, from 1995-2002. The net effect of UVR on biological systems is a result of the balance of damage and repair which depends on intensity and duration of irradiance and...

Solar Ultraviolet Radiation (UVR), which is identified as a major environmental health hazard, responsible for variety of photochemical reactions with direct effects on urban and aquatic ecosystems, human health, plant growth, the deterioration industrial systems. Ground measurements total solar UVR are scarce, low spatial temporal coverage around world, mainly due to measurement equipment main...

Excessive exposure of skin to ultraviolet radiation (UVR) has dramatic clinical effects in humans, and it is a significant public health concern. Discomfort and sensory changes caused by skin sunburn are the main common features experienced by many of us, a phenomena triggered by the combination of long and short wavelengths radiation (UVA and UVB, respectively). Although the biological process...

PURPOSE To study the possible potentiation of the carcinogenic effects of ultraviolet radiation associated with an organophosphate pesticide. METHODS Forty Wistar rats were assigned into four groups (n=10 each) randomized according to the procedures: group A received only UVR-B radiation; group B, UVR-B for eight weeks followed by a seven week period of pesticide exposure; group C, UVR-B + pe...

In shallow subarctic ponds Daphnia and their algal food are often exposed to solar ultraviolet radiation (UVR). It was previously demonstrated that direct exposure of Daphnia to UVR may result in sublethal damage to Daphnia‘s intestinal system. This led to the hypothesis that, as consequences of such exposures, Daphnia may be experiencing a situation similar to starvation. We examined, in contr...