Although ex vivo expanded T cells are currently widely used in pre-clinical and clinical trials, the complexity of manufacture remains a major impediment for broader application. In this review we discuss current protocols for the ex vivo expansion of virus- and tumor-specific T cells and describe our experience in manufacture optimization using a gas-permeable static culture flask (G-Rex). Thi...

Rolls-Royce today is an increasingly global business, supplying integrated power systems to a wide variety of customers for use on land, at sea and in the air. Its reputation for 'delivering excellence' to these customers has been built largely on its gas turbine technology portfolio, and this reputation relies on the quality of the company's expertise in design, manufacture and delivery of ser...

fundamental understanding of the goaf gas distribution in a gassy coal mine is necessary for developing effective goaf gas drainage strategies in the longwall coal mine. the goaf gas was subjected to the surface and body forces that were classified depending upon whether they acted on the surface area or the volume of the gas element. of these forces, the body forces were more predominant in di...

To meet the need of gas monitoring in mine laneway environment, designed a gas monitoring system based on ZigBee technology, the chip of CC2430 is the core, and this system conquers the defect of wired sensor networks and avoids the high-energy cost of other wireless technology.The hardware design and software design method had been presented, and the result had been given. This system has the ...

The mortality risk of iron ore (haematite) miners between 1970 and 1982 was investigated in a retrospective cohort study of workers from two mines, Longyan and Taochong, in China. The cohort was limited to men and consisted of 5406 underground miners and 1038 unexposed surface workers. Among the 490 underground miners who died, 205 (42%) died of silicosis and silicotuberculosis and 98 (20%) of ...

A leaking water pipe bursting high pressure water jet in the soil will create slurry erosion which will eventually erode the adjacent natural gas pipe, thus causing its failure. The standard 300 mm safety distance used to place natural gas pipe away from water pipeline facilities needs to be reviewed to consider accidental damage and provide safety cushion to the natural gas pipe. This paper pr...

Methane is a powerful greenhouse gas and the principal component of natural gas. Coal seams often contain significant quantities of methane, and underground coal mines must ensure that methane released into the mine during coal extraction does not build to dangerous levels. This is accomplished in part through the use of large-volume ventilation systems that remove methane from the mine and rel...

The TPC is the central detector of the CERN-LHC experiment ALICE. It is the largest TPC ever built with a gas volume of ~90 m and 557568 readout channels. The LHC is scheduled to commence operation in 2007 with pp-collisions. Before installation underground inside the ALICE L3 magnet, the TPC including its auxiliary systems and services, i.e., gas system, temperature monitoring system, drift ve...