The essentially planar pyrazole ring (r.m.s. deviation = 0.013 Å) in the title hemisolvate, C(31)H(33)N(7)S·0.5C(3)H(7)NO, is almost coplanar with the pendant thio-urea residue [N-N-C-S torsion angle = -173.2 (4)°] and slightly twisted with respect to the triazole ring [dihedral angle = 7.7 (3)°]. An intra-molecular thio-urea-pyrazole N-H⋯N hydrogen bond, via an S(5) loop, is formed. Supra-mole...

In the title thio-urea derivative, C(10)H(17)N(3)O(2)S, the carboxyl group and the least-squares plane through the cyclo-hexyl ring are twisted out of the plane through the central CN(3)S residue; the respective dihedral angles are 7.18 (8) and 62.29 (4)°. The conformation about the azomethine bond [1.275 (2) Å] is E. The NH groups are anti, with one forming an intra-molecular N-H⋯N hydrogen bo...

The title bromide salt, [Cr{CO(NH2)2}6](Cr2O7)Br·H2O, is isotypic to the corresponding chloride salt. Within the complex cation, the Cr(III) atom is coordinated by six O atoms of six urea ligands, displaying a slightly distorted octa-hedral coordination environment. The Cr-O bond lengths involving the urea ligands are in the range 1.9534 (13)-1.9776 (12) Å. The Cr2O7 (2-) anion has a nearly sta...

The title complex, [NiCl(2)(CH(4)N(2)S)(2)], has been synthesized from the previously reported (diamino-methyl-idene)sulfonium chloride-thio-urea (3/2) salt [Zouihri (2012b ▶). Acta Cryst. E68, o257]. The Ni(II) ion is coordinated in a distorted tetra-hedral geometry by two mol-ecules of thio-urea [Ni-S = 2.3079 (7) and 2.3177 (6) Å] and two chloride anions [Ni-Cl = 2.2516 (7) and 2.2726 (7) Å]...

In the title compound, C17H20ClN3OS, the mean plane of the central thio-urea core makes dihedral angles of 26.56 (9) and 47.62 (12)° with the mean planes of the chromene moiety and the cyclo-hexyl ring, respectively. The cyclo-hexyl ring adopts a chair conformation. The N-H atoms of the thio-urea unit adopt an anti conformation. The chromene group is positioned trans, whereas the cyclo-hexyl ri...

In the title compound, C12H14Cl2N2O2S, the mol-ecule adopts a cis conformation with respect to the di-chloro-benzoyl group against the thiono group about the C-N bond. However, the di-chloro-benzene group and the thio-urea moiety are twisted by 75.41 (8)°. An intra-molecular N-H⋯O hydrogen bond occurs between the amido H atom and hydroxyl O atom. In the crystal, O-H⋯S and O-H⋯O hydrogen bonds l...

The benzene and phenyl rings in the title compound, C(14)H(9)Cl(3)N(2)OS, form a dihedral angle of 40.98 (6)°. The mol-ecule exists in the thione form with typical thio-urea C-S [1.666 (2) Å] and C-O [1.227 (3) Å] bond lengths as well as shortened C-N bonds [1.345 (3) and 1.386 (2) Å]. An intra-molecular N-H⋯O hydrogen bond stabilizes the mol-ecular conformation. In the crystal, pairs of N-H⋯S ...

In the title salt, [Ag(CH4N2S)2(PPh3)2]NO3, the Ag(I) atom is coordinated by two thio-urea S atoms and two tri-phenyl-phosphane P atoms in a distorted tetra-hedral geometry, with bond angles in the range 102.90 (4)-123.29 (4)°. The Ag-S=C bond angles are 101.75 (19) and 111.29 (18)°. In the crystal, the component ions are linked by C-H⋯O, C-H⋯S, N-H⋯O and N-H⋯S hydrogen bonds, generating (10-1)...

Conditions leading to cleavage of all of the disulfide bridges in ribonuclease and several other proteins (0.32 M Z-mercaptoethanol in 8 M urea) caused in papain only partial reduction of the disulfide bonds. Electrophoretic studies indicated that alkylation of the partially reduced derivative yielded a unique molecular species (3-RCM papain) in which one specific disulfide bond had been split,...