Spontaneous rupture of the urinary bladder associated with bladder cancer is very rare. Its signs and symptoms are those of peritonitis, and thus non-specific, possibly causing diagnostic confusion. A 69-year-old man with a history of macrohematuria and possible neurogenic bladder presented with signs of peritonitis. Laparotomy revealed bladder rupture associated with squamous cell carcinoma of...

Background: E-cadherin is a trans-membrane glycoprotein that plays a critical role in many aspects of cell adhesion as well as establishment and maintenance of epithelial cell polarity. Loss of the adhesive function of E-cadherin seems to promote invasive and metastatic properties of neoplastic cells. Objectives: The present study is a retrospective study aiming to evaluate the loss of E-cadher...

Bladder cancer is the 10th most common in both males and females with a ratio of 3:1. About 75% bladder cancers are non-muscle invasive (NMIBC). The aim this study was to identify characteristics Non-Muscle Invasive Cancer (NMIBC) patients treated Dr. Hasan Sadikin General Hospital as one tertiary hospitals Indonesia. This retrospective descriptive that involved reviewing medical records diagno...

Several drugs have shown in vitro and in vivo pharmacological activity against urinary bladder cancer. This review aims at compiling the different drugs evaluated in in vitro and in vivo models of urinary bladder cancer and to review the advantages and limitations of both types of models, as well as the different methodologies applied for evaluating antineoplastic drug activity. Cancer is one o...

BACKGROUND Bladder cancer is the most frequent genitourinary malignancy in Iran. Environmental and genetic factors are the two factors linked with bladder cancer expansion. The aim of this study was to investigate the role of PTEN gene and environmental risk factors on the progression and prognosis of bladder cancer. METHODS We evaluated 55 tumor specimens and 66 bladder mucosa samples of non...

BACKGROUND The frequency of over-expression of human epidermal growth factor receptor-2 (HER-2) in bladder cancer is one of the highest among all human malignancies. This over-expression is thought to play a role in aberrant proliferation of cancer cells. Studies on HER-2 expression in bladder carcinoma have shown heterogeneous results. PURPOSE The aim of the study was to evaluate the status ...

The overall pathogenesis of bladder cancer is still unknown. microbiota has been shown to play a critical role in the development different types cancer. Nevertheless, not fully discovered. This review aims assess urinary, vaginal, and intestinal analyzed from bacterial, viral, fungal compartments patients compared with controls reveal possible differences. A systematic according PRISMA guideli...

Bladder cancer continues to be one of the most common malignancies. Those who have been already diagnosed are at high risk for recurrence, especially if the pathology demonstrates high-grade disease. Diagnosis and surveillance is reliant on invasive evaluation with cystoscopy. Urinary cytology has been used to aid in diagnosis, but its use is limited. Other assays have been developed that may a...

abstract: urinary bladder hemangiomas are very rare and accounting for 0.6% of all urinry bladder toumors. it is rare cause of hematuria. a 8-year old boy presented with painless gross hematuria for one week. he had past history of this problem 5 months ago. physical examination revealed no unusual findings. sonogeraphy and ct scan showed intraluminal bladder mass with exteravesical cyctic comp...

inTrodUcTion Radical cystectomy for bladder and urinary diversion is considered the gold standard for treatment of muscular invasive bladder cancer or high‐risk nonmuscular invasive bladder cancer. Urinary diversion is usually classified into three types: orthotopic neobladder, ileal conduit or sigmoid conduit, and cutaneous ureterostomy.[1] Orthotopic neobladder is a better choice for urinary ...