The present study was undertaken to determine whether improvement of hyperglycemia alters calcium and phosphorus handling, parathyroid hormone (PTH) secretion and bone turnover in patients with non-insulin-dependent diabetes mellitus (NIDDM). We measured serum and urinary mineral levels, serum intact PTH and osteocalcin on admission and at discharge (38 +/- 3 days later, Means +/- SEM) in 28 pa...

OBJECTIVE X-linked hypophosphatemia (XLH) is characterized clinically by rickets, hypophosphatemia, and hyperphosphaturia. Conventional treatment of XLH with oral phosphate and vitamin D is associated with increased urinary calcium excretion and nephrocalcinosis. Thiazide diuretics decrease urinary calcium excretion. The objective of this study was to determine the effect of thiazide diuretics ...

Several studies have shown an increase in urinary calcium excretion in response to a calcium load. However, because of the inverse changes in PTH levels with a calcium load, the effect of changes in serum calcium per se on its own excretion is unclear in humans. In this study we used a PTH clamp protocol to further characterize calcium-regulated renal calcium and magnesium handling and the rela...

We evaluated the crystallization of calcium oxalate (CaOx) in undiluted urine, collected 3 hours after intake of a test meal by healthy males. In two experiments in vitro, either the total citrate concentration was increased (urine A) or the pH was elevated (urine B). In addition, in three clinical trials, the bioequivalence of orally taken potassium citrate (PC) and potassium-sodium citrate (P...

abstract introduction : conjugated linoleic acid (cla) has been shown to positively influence on calcium and bone metabolism in experimental animals and cell culture, but there are limited human data available. material and methods : this double-blind, placebo-controlled trial study was done on 76 healthy post-menopausal women (aged 55.1) which randomly assigned to receive daily four cla capsul...

Oral doses of caffeine increase the urinary excretion of calcium, magnesium, sodium and chloride for at least 3 h after consumption. The hypercalciuric effect can be blocked by adenosine receptor agonists. The effect is proportional to dose per lean body mass and no adaptation to the urinary losses occurs with continuing consumption of caffeine. Uncompensated losses of calcium would be a risk f...

Background: Osteoporosis is one of the prevalent diseases post-Menopausal women. Hence to evaluate severity osteoporosis serum calcium, ALP and urinary hydroxyproline used as bone resorption marker.Method: 30 post-menopausal women with were compared healthy pre-menopausal 25-40 years Random Blood sample collected from venipuncture centrifuged get serum. Fasting Urine was 1.2 drops 6 N HCI added...

Clinical, biochemical, and ultrasonographic findings in 91 consecutive children presenting with hypercalciuria were analyzed along with the results of treatment to determine the clinical profile of hypercalciuria and its outcome. Hypercalciuria was common in children aged 1-5 years (39.6%), and hematuria was the most frequent symptom. There was no significant difference between 24-hour urinary ...